Japanese
Title肝・胆道核医学診断
Subtitle総説
Authors油野民雄*
Authors(kana)
Organization*旭川医科大学放射線科
Journal核医学
Volume32
Number6
Page599-603
Year/Month1995/6
Article報告
Publisher日本核医学会
Abstract「要旨」機能的画像診断法である特徴を活かして, 肝・胆道領域でも核医学検査が施行されることが決して少なくないことを強調したい. 肝シンチグラフィ用放射性医薬品は局在原理の相違により99mTc-コロイド, 99mTc-PMTおよび99mTc-GSAに大別されるが, 実際の評価に際しては検査目的に応じた適切な薬剤の選択が必要となる. 一般に, 肝疾患の慢性化の進行状態および肝硬変への進展の評価では99mTc-コロイド, 重症度および予後の推定では99mTc-PMTまたは99mTc-GSA, さらに予備能の評価では99mTc-GSAの使用が適切である. 小葉胆管から総胆管に至るまでの胆道通過性の評価には, 99mTc-PMTが用いられる. 胆道シンチグラフィは, 現在急性胆嚢炎診断における最も信頼性の高い検査であり, そのほか胆汁うっ滞, 体質性黄疸, 胆汁漏出, 胆道運動機能異常症, 乳児黄疸などの評価にも施行されている.
Practice臨床医学：一般
KeywordsRadionuclide imaging, Hepatic scintigraphy, Hepatobiliary scintigraphy, Hepatobiliary diseases.
English
TitleRadionuclide Imaging in Hepatobiliary Disease
SubtitleReview
AuthorsTamio ABURANO
Authors(kana)
OrganizationDepartment of Radiology, Asahikawa Medical College
JournalThe Japanese Journal of nuclear medicine
Volume32
Number6
Page599-603
Year/Month1995/6
ArticleReport
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractPresently, radionuclide imaging in hepatobiliary disease is mainly used to evaluate the functional aspect in hepatobiliary disease. For the evaluation of hepatic function, three kinds of radiopharmaceuticals are now commercially available: these are the Kupffer-cell oriented radiotracer of 99mTc-colloid, the hepatocyte oriented radiotracer of 99mTc-PMT, and the receptor-binding radiopharmaceutical of 99mTc-GSA. These radiopharmaceuticals must be properly used, according to the purposes. 99mTc-PMT can be used to determine the degree of functional disorder in acute hepatic disease and evaluate the severity of diffuse hepatic disease, whereas 99mTc-colloid can effectively evaluate the potential etiology of the disease process and its chronicity. And 99mTc-GSA may also be used to evaluate the severity of the disease. In particular, the hepatic functional reserve must be evaluated with 99mTc-GSA. The biliary patency from the intrahepatic bile canaliculi to the common bile duct can be effectively evaluated with 99mTc-PMT. The diagnosis of acute cholecystitis is most reliably made by radionuclide imaging. And radionuclide imaging is sometimes to be used for the differentiation of cholestasis. In particular, the discrimination among the disease entities of chronic intermittent intrahepatic cholestasis including primary biliary cirrhosis, primary sclerosing cholangitis and juvenile intrahepatic bile duct hypoplasia can be made. Moreover, it is also be used in evaluating constitutional hyperbilirubinemia, biliary leakage, infantile jaundice and gallbladder or syphinctor Oddi motor dysfunction.
PracticeClinical medicine
KeywordsRadionuclide imaging, Hepatic scintigraphy, Hepatobiliary scintigraphy, Hepatobiliary diseases.

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