| Japanese |
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| Title | 心拍同期法併用による99mTc-MIBI, 123I-BMIPP 2核種同時心筋SPECTデータ収集 - 虚血性心疾患における臨床的有用性の検討 - |
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| Subtitle | 原著 |
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| Authors | 汲田伸一郎*, 水村直*, 木島鉄仁*, 町田稔*, 隈崎達夫*, 哲翁弥生**, 酒井俊太**, 草間芳樹**, 宗像一雄** |
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| Organization | *日本医科大学放射線科, **第一内科 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 6 |
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| Page | 547-555 |
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| Year/Month | 1995/6 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」虚血性心疾患25例を対象として99mTc-MIBI, 123I-BMIPPを用いた2核種同時心筋SPECTデータ収集を行った. 99mTc-MIBI 555 MBq, 123I-BMIPP 148 MBqの静注1時間後より心電図同期併用の心筋シンチグラフィを施行, 収集時エネルギーピーク値を99mTc:140 KeV, 123I:164 KeVに設定した. 得られたMIBI/BMIPP心筋SPECT像の画質はおおむね良好であり, 臨床診断に支障をきたさないものであった. 心拍同期MIBIシンチグラフィの拡張末期および収縮末期像を用い解析した左室収縮能値%wall thickeningと, MIBI/BMIPP像におけるseverity scoreとの比較では, それぞれr=-0.70, -0.72と良好な逆相関を認めた. 心電図同期併用のMIBI/BMIPP 2核種同時収集SPECTは, 同時に同一SPECT上にて, 心筋血流, 心筋脂肪酸代謝さらには左室収縮能をも評価できる臨床的に有用な検査手法であると思われる. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-MIBI, 123I-BMIPP, Simultaneous dual isotope acquisition, ECG-gated myocardial scintigraphy. |
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| English |
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| Title | ECG-Gated Dual Isotope Myocardial SPECT with 99mTc-MIBI and 123I-BMIPP in Patients with Ischemic Heart Disease |
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| Subtitle | Original Articles |
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| Authors | Shin-ichiro KUMITA*, Sunao MIZUMURA*, Tetsuji KIJIMA*, Minoru MACHIDA*, Tatsuo KUMAZAKI*, Yayoi TETSUOU**, Shunta SAKAI**, Yoshiki KUSAMA**, Kazuo MUNAKATA** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **First Department of Internal Medicine, Nippon Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 6 |
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| Page | 547-555 |
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| Year/Month | 1995/6 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | Simultaneous dual-isotope SPECT with 99mTc-methoxy isobutyl isonitrile (MIBI) and 123I-β-methyl iodophenyl-pentadecanoic acid (BMIPP) was performed in 25 patients with ischemic heart disease. ECG-gated myocardial SPECT was acquired following the injection of MIBI (555 MBq) and BMIPP (148MBq). Both MIBI and BMIPP scans provided high-quality myocardial images. Then, myocardial count increase rate (%WT=ES-ED/ED×100) was calculated as an index of left ventricular contraction using MIBI gated SPECT data. The %WT was well correlated with severity scores of both MIBI image (r=-0.70) and BMIPP image (r=-0.72). Thus, ECG-gated dual-isotope SPECT with MIBI and BMIPP was considered to be useful method for assessment of left ventricular contraction as well as myocardial perfusion and fatty acid metabolism. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-MIBI, 123I-BMIPP, Simultaneous dual isotope acquisition, ECG-gated myocardial scintigraphy. |
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