| Japanese |
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| Title | 99mTc-DMSA腎シンチグラムによる定量的分腎機能の評価 - 131I-OIHレノグラムとの比較検討 - |
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| Subtitle | 技術報告 |
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| Authors | 駒井哲之*, 外山宏*, 竹内昭**, 横山貴美江***, 古賀佑彦* |
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| Authors(kana) | |
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| Organization | *藤田保健衛生大学医学部放射線科, **衛生学部診療放射線技術学科, ***病院放射線部 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 4 |
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| Page | 427-433 |
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| Year/Month | 1995/4 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」99mTc-2,3-di-mercapto-succinic acid腎摂取率 (DMSA) による定量的分腎機能の評価を行った. 対象は211症例 (1〜87歳) と正常ボランティア4人で, 同日に131I-orthoiodohippurateレノグラム (OIH) を行い, 両者を比較した. OIHのパターンが正常型を示し, 腎機能が正常なものを正常群として, 正常ボランティアとともに年齢との相関性を見たところ, 有意な負の相関を示した. OIHのパターン上, 高度機能低下型および無機能型は正常型に比べ有意なDMSAの低下を認め, 軽度機能低下型から無機能型までの各群間にDMSAの有意差を認めた. 代償性肥大のある症例では肥大腎群が萎縮腎群に対し有意なDMSAの増加を示し, 肥大腎の機能的な代償を定量的に示すことができることが示唆された. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-2,3-di-mercapto-succinic acid (DMSA), 131I-orthoiodohippurate (OIH), Quantitative analysis, Individual renal function, Renoscintigram |
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| English |
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| Title | Quantitative Analysis of Individual Renal Function Using 99mTc-DMSA Scintigram - Comparison with 131I-OIH Renogram - |
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| Subtitle | |
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| Authors | Satoshi KOMAI*, Hiroshi TOYAMA*, Akira TAKEUCHI**, Kimie YOKOYAMA***, Sukehiko KOGA* |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Fujita Health University School of Medicine, **Faculty of Radiological Technology, Fujita Health University School of Health Sciences, ***Section of Radiology, Fujita Health University Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 4 |
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| Page | 427-433 |
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| Year/Month | 1995/4 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] 99mTc-2,3-di-mercapto-succinic acid (DMSA) is able to be used for the quantitative analysis of individual renal function by calculating the uptake ratio. The purpose of this study is to assess the clinical feasibility of DMSA uptake ratio as compared with 131I-ortho-iodo-hippuran (OIH) renogram pattern. Two hundred eleven cases (191 patients, 1 to 87 years old) with renal disorders and 4 normal volunteers (27.8+-2.4 years old) were studied. Just prior to the DMSA study in the same day, OIH renogram was carried out. They were divided into 6 types by OIH renogram patterns. In 24 cases of normal renogram pattern and normal blood data who were defined as the normal group and 4 normal volunteers, DMSA uptake ratio showed negative correlation with increasing age (r=0.61, p<0.05). Patients of the severe impaired functioning and the non functioning patterns showed significantly decreased DMSA uptake ratios as compared with the normal pattern. There was also a significant difference in DMSA uptake between impaired functioning patterns. Compensative hemi-hypertrophy kidneys showed significantly higher DMSA uptake ratios than those of atrophic kidneys. The possibility of the quantitative analysis of the functional compensation was presumed. In conclusion, quantitative analysis of individual renal function using DMSA uptake ratio is considered to be useful to evaluate the renal functional reserve. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-2,3-di-mercapto-succinic acid (DMSA), 131I-orthoiodohippurate (OIH), Quantitative analysis, Individual renal function, Renoscintigram |
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