| Japanese |
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| Title | 99mTc-tetrofosmin運動負荷心筋シンチグラフィを用いた心筋viabilityの評価 - 再静注201Tl心筋シンチグラフィとの比較 - |
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| Subtitle | 原著 |
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| Authors | 小林秀樹*, 河口正雄**, 岡俊明**, 井上征治**, 半田淳**, 浅野竜太**, 松本延介**, 住吉徹哉**, 細田瑳一**, 日下部きよ子* |
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| Authors(kana) | |
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| Organization | *東京女子医科大学放射線科, **循環器内科 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 4 |
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| Page | 367-375 |
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| Year/Month | 1995/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」陳旧性心筋梗塞21例を対象としてTetrofosmin運動負荷心筋シンチグラフィ (TF) を施行し, 心筋viability評価について検討した. 再静注法を用いた201Tl運動負荷心筋シンチグラフィ (TL) により心筋viabilityありと判定された16例中の15例は, TFで心筋viabilityありと判定された. TL再静注像とTF安静時像の梗塞部%RI uptakeは, 52±16% vs. 47±16%とTF像の%RI uptakeが低値であったが, %RI uptakeの差が5%以下の症例が15例, 10%以下が3例と多数例でほぼ同等のRI集積を呈していた. TF安静投与後の早期像と遅延像を比較すると, 再分布はいずれの症例にも全く認められず, 逆再分布所見が19例中の4例で認められた. 以上の結果から, TFを用いた負荷像, 安静像の2回撮像による心筋viability評価は, 再静注法を用いたTLに匹敵する良好な判定が可能と考えられた. また心筋viability評価において, TF安静投与後の遅延像の撮像は不要であった. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-tetrofosmin, Myocardial viability, 201Tl reinjection method, Reverse redistribution, Redistribution |
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| English |
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| Title | Identification of Viable Myocardium Using 99mTc-Tetrofosmin Scintigraphy - Comparison with 201Tl Redistribution-Reinjection Images - |
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| Subtitle | Original Articles |
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| Authors | Hideki KOBAYASHI*, Masao KAWAGUCHI**, Toshiaki OKA**, Seiji INOUE**, Jun HANDA**, Ryuta ASANO**, Nobusuke MATSUMOTO**, Tetsuya SUMIYOSHI**, Saichi HOSODA**, Kiyoko KUSAKABE* |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Tokyo Women's Medical College Hospital, **Department of Cardiology, Tokyo Women's Medical College Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 4 |
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| Page | 367-375 |
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| Year/Month | 1995/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] The purpose of this study was to clarify the diagnostic value of identifying viable myocardium using 99mTc-Tetrofosmin scintigraphy. Twenty-one patients with chronic coronary artery disease were studied using 201Tl exercise myocardial scintigraphy with reinjection and 99mTc-Tetrofosmin exercise myocardial scintigraphy. All patients had a history of old myocardial infarction. For 99mTc-Tetrofosmin scintigraphy, 222 MBq of 99mTc-Tetrofosmin was injected during exercise, and exercise images were obtained 20 min thereafter. Three hours later, 666 MBq of 99mTc-Tetrofosmin was injected at rest, and images were obtained 40 min and 220 min later. Myocardial viability in the 99mTc-Tetrofosmin scintigraphy was estimated as fill-in findings (FF) or over 50% of %RI uptake (%TF) in the rest image. Myocardial viability in the 201Tl scintigraphy was estimated as redistribution (RD), fill-in findings in the reinjection image (FR) or over 50% of %RI uptake in the reinjection image (%TL). Sixteen of the 21 patients (76%) who underwent 201Tl scintigraphy (RD 10, FR 3, %TL 3 cases) and 15 of the 21 patients (71%) who underwent 99mTc-Tetrofosmin scintigraphy (FF 11, %TF 4 cases) had viable myocardium in the infarcted area. A comparison between the 99mTc-Tetrofosmin rest images obtained 40 min after the injection and that of 220 min revealed no redistribution findings. The %RI uptake of the infarcted area in the resting 99mTc-Tetrofosmin image (47+-16%) was slightly lower than that in the 201Tl reinjection image (52+-16%). In conclusion, viable myocardium was as clearly identified by 99mTc-Tetrofosmin, as by 201Tl scintigraphy. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-tetrofosmin, Myocardial viability, 201Tl reinjection method, Reverse redistribution, Redistribution |
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