Japanese
Title急性心筋梗塞における123I-BMIPPシンチグラムと左室機能との関連
Subtitle原著
Authors広瀬義晃*, 石田良雄*, 林田孝平*, 植原敏勇**, 西村恒彦**
Authors(kana)
Organization*国立循環器病センター放射線診療部, **大阪大学医学部バイオメディカル教育研究センタートレーサ情報解析
Journal核医学
Volume32
Number3
Page281-286
Year/Month1995/3
Article原著
Publisher日本核医学会
Abstract「要旨」123I-BMIPPシンチグラムと左室機能との関連について定量的に検討した. 対象は急性心筋梗塞25例である. 123I-BMIPPと201Tlの2核種同時投与による安静時心筋SPECTを施行した. 123I-BMIPPと201Tlの障害領域をブルズアイ表示にて定量的に求め, 左室駆出率, 壁運動と対比した. 123I-BMIPPは201Tlより大きな欠損を示し, その比は1.80であった. この欠損の大きさの不一致は, 冠血行再建術を施行した症例で明瞭であった. また, 123I-BMIPPは201Tlよりも左室駆出率と高い相関があった (r=-0.54). 123I-BMIPPの集積低下は局所壁運動の低下とよく一致し, セグメントの一致率は79%, 不一致率は14%であった. 発症直後と4週間後の左室駆出率の差は123I-BMIPPと201Tlの欠損の拡がりの差と正相関 (r=0.55) し, 123I-BMIPPと201Tlの乖離の程度が左室機能改善の程度を予測しうることが示唆された.
Practice臨床医学:一般
Keywords123I-BMIPP, Acute myocardial infarction, Left ventricular ejection fraction, Wall motion, Bull's eye map
English
TitleRelationship between 123I-BMIPP Imaging and Cardiac Function in Acute Myocardial Infarction
Subtitle
AuthorsYoshiaki HIROSE*, Yoshio ISHIDA*, Kohei HAYASHIDA*, Toshiisa UEHARA**, Tsunehiko NISHIMURA**
Authors(kana)
Organization*Department of Radiology, National Cardiovascular Center, **Biomedical Research Center, Osaka University Medical School
JournalThe Japanese Journal of nuclear medicine
Volume32
Number3
Page281-286
Year/Month1995/3
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] We evaluated the relationship between free fatty acid metabolism using 123I beta-methyl-iodophenyl pentadecanoic acid (BMIPP) and cardiac function in acute myocardial infarction. Twenty-five patients were examined with 123I-BMIPP and 201Tl dual SPECT. The 123I-BMIPP images were compared with the 201Tl images and the left ventricular wall motions. The 123I-BMIPP images showed a larger uptake defect than the 201Tl images. This was marked in the patients after revascularization therapy. The uptake decrease of 123I-BMIPP was in good agreement with the decrease in regional wall motion. The incidence of accordance was 79% of the wall segments. The correlation between 123I-BMIPP defect size and ejection fraction was higher (r=-0.54) than that of 201Tl (r=-0.44). Subtraction of ejection fractions four weeks and soon after infarction correlated well with the subtraction of 123I-BMIPP and 201Tl defect sizes (r=0.55). In conclusion, 123I-BMIPP is more closely related to wall motion, than 201Tl and might be valuable in predicting the functional improvement of acute myocardial infarction.
PracticeClinical medicine
Keywords123I-BMIPP, Acute myocardial infarction, Left ventricular ejection fraction, Wall motion, Bull's eye map

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