| Japanese |
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| Title | 急性心筋梗塞後stunningにおける201Tlと123I-BMIPPの画像推移の比較検討 |
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| Subtitle | 原著 |
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| Authors | 中野顯*, 近藤真言*, 徳永智*, 秋山清純**, 森佳久**, 野末恭弘**, 牧田俊則*, 谷尾仁志*, 霜野幸雄* |
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| Authors(kana) | |
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| Organization | *市立島田市民病院循環器科, **放射線科 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 3 |
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| Page | 227-233 |
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| Year/Month | 1995/3 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」急性心筋梗塞後stunningの局所心機能回復過程における虚血性脂肪酸代謝障害の推移について, 123I-BMIPP心筋SPECTを用い, 201Tl心筋SPECTと心臓超音波検査法 (UCG) との比較で検討した. 対象は初回発症, 一枝病変の急性心筋梗塞で再灌流成功例15症例. 全例に対し急性期および慢性期にUCG, 123I-BMIPP心筋SPECT, 201Tl心筋SPECTを施行. 慢性期の局所壁運動は症例別では15例中10例で改善を認め, segment別では100 segment中26 segmentで改善を認めた. この中で123I-BMIPPの心筋集積改善を認めたのは, 症例別では, 10.0% (1/10) で, segment別では, わずか3.8% (1/26) にすぎず, 201Tlの80.0% (8/10), 92.3% (24/26) とは対照的な結果であった (p<0.01, p<0.0001). 以上より, 123I-BMIPPの心筋集積異常は壁運動異常・201Tl心筋集積異常よりもさらに遷延すると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Stunned myocardium, Acute myocardial infarction, Fatty acid metabolism, 201Tl, 123I-BMIPP |
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| English |
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| Title | Serial Change of 123I-BMIPP SPECT Imaging during Recovery from Stunned Myocardium after Acute Myocardial Infarction - Correlation with 201Tl and Two-Dimensional Echocardiography - |
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| Subtitle | Original Articles |
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| Authors | Akira NAKANO*, Makoto KONDO*, Satoshi TOKUNAGA*, Kiyozumi AKIYAMA**, Yoshihisa MORI**, Yasuhiro NOSUE**, Toshinori MAKITA*, Hitoshi TANIO*, Yukio SHIMONO* |
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| Authors(kana) | |
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| Organization | *Division of Cardiology, Shimada Municipal Hospital, **Division of Radiology, Shimada Municipal Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 3 |
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| Page | 227-233 |
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| Year/Month | 1995/3 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Using 123I-β-methyl iodophenyl pentadecanoic acid (123I-BMIPP), we investigated changes in myocardial fatty acid metabolism at recovery from stunned myocardium after acute myocardial infarction (AMI), correlation with recovery of regional wall motion and thallium-201 (201Tl) distribution in particular. The subjects were 15 patients who underwent successful reperfusion therapy after the first onset of AMI. None of the patients had multi-vessel disease or ischemic episode during their clinical course. Patients underwent 123I-BMIPP scintigraphy, 201Tl scintigraphy and two-dimensional echocardiography during the acute and chronic phases. Then, we compared regional wall motion with distribution of 123I-BMIPP and 201Tl. Regional wall motion and SPECT were evaluated by the established 16 segment model. In patients, showing serial improvement in regional wall motion, there was 80.0% (8/10) showed normal 201Tl distribution during the acute phase or normalized during the chronic phase. However, distribution of 123I-BMIPP normalized only in 10.0% (1/10) of this group. In examination of each segment that showed serial improvement in regional wall motion, 92.3% (24/26) of these segments showed normal distribution of 201Tl during the acute phase or normalized distribution during chronic phase, despite distribution of 123I-BMIPP improved in only 3.8% (1/26) of these segments. These indicate that, in the process of recovery from myocardial stunning after AMI, abnormal distribution of 123I-BMIPP continued longer than abnormal distribution of 201Tl. |
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| Practice | Clinical medicine |
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| Keywords | Stunned myocardium, Acute myocardial infarction, Fatty acid metabolism, 201Tl, 123I-BMIPP |
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