| Japanese |
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| Title | 99mTc-MAG3と131I-OIH同時投与による両薬剤の比較検討 |
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| Subtitle | 原著 |
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| Authors | 橋本禎介*, 松本一宏*, 石橋了知*, 橋本順*, 国枝悦夫*, 岩崎隆一郎*, 三宮敏和*, 中村佳代子*, 久保敦司* |
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| Organization | *慶應義塾大学医学部放射線科 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 2 |
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| Page | 139-146 |
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| Year/Month | 1995/2 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」新しい99mTc標識腎動態機能イメージング剤である99mTc-MAG3のOIH製剤との差を評価するために各種腎疾患を有する16症例を対象として2核種同時収集法にて99mTc-MAG3と131I-OIHとを同時投与し両薬剤の比較検討を行った. 99mTc-MAG3と131I-OIHのレノグラムパターンは16例 (32腎) 全例で同じパターンを示し, 不一致症例は認められなかった. レノグラムのTmax, T2/3, T1/2は両薬剤の間でいずれも有意 (p<0.001) な相関を示し, 平均値は99mTc-MAG3の方が有意に (p<0.05, 0.001) 延長していたがその傾向に症例ごとの大きな差はなかった. 以上より99mTc-MAG3によるレノグラムは131I-OIH製剤に比べやや排泄が延長しているがレノグラムパターンとしては差がないことが確認された. |
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| Practice | 臨床医学：一般 |
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| Keywords | Renogram, 99mTc-MAG3, 131I-OIH, Simultaneous injection |
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| English |
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| Title | Evaluation of Renal Function Using 99mTc-MAG3 Comparison with 131I-OIH by Simultaneous Dual Energy Peak Acquisition Method |
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| Subtitle | Original Articles |
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| Authors | Teisuke HASHIMOTO, Kazuhiro MATSUMOTO, Ryochi ISHIBASHI, Ryuichiro IWASAKI, Toshikazu SANMIYA, Jun HASHIMOTO, Etsuo KUNIEDA, Kayoko NAKAMURA, Atsushi KUBO |
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| Authors(kana) | |
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| Organization | Department of Radiology, School of Medicine, Keio University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 2 |
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| Page | 139-146 |
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| Year/Month | 1995/2 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] A newly developed 99mTc-labeled renal scintigraphic and renographic agent, 99mTc-mercaptoacetyl-triglycine (99mTc-MAG3) was studied clinically and compared with 131I-OIH in 16 patients with various renal and urinary tract disorders. The abdominal aorta and the common iliac artery were clearly visualized in the vascular phase. The renogram patterns showed the same pattern in all cases. The parameters on the renogram such as Tmax, T2/3, T1/2 were compared. The highly significant correlations of Tmax, T2/3 and T1/2 were observed between 99mTc-MAG3 and 131I-OIH with correlation coefficient of 0.982, 0.907, 0.990, respectively. In all cases, excretion of 99mTc-MAG3 was slower than that of 131I-OIH and the ratios of Tmax, T2/3 and T1/2 between 99mTc-MAG3 and 131I-OIH were 1.113+-0.121, 1.277+-0.247, 1.179+-0.075, respectively. It is concluded that 99mTc-MAG3 is useful renal imaging agent as an alternative to 131I or 123I-OIH. |
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| Practice | Clinical medicine |
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| Keywords | Renogram, 99mTc-MAG3, 131I-OIH, Simultaneous injection |
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