| Japanese |
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| Title | 連続回転収集機能を有する3検出器型SPECT装置を使用したDynamic SPECT像による肺局所133Xeガス洗い出し像の検討 |
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| Subtitle | 原著 |
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| Authors | 菅一能*, 西垣内一哉*, 久米典彦*, 高野勝之*, 小池晋司*, 松本常男*, 松永尚文* |
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| Organization | *山口大学医学部放射線医学教室 |
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| Journal | 核医学 |
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| Volume | 32 |
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| Number | 1 |
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| Page | 51-61 |
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| Year/Month | 1995/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」Xenon-133 (133Xe) ガス洗い出し法は肺局所換気異常を鋭敏に検出する. しかし従来のSPECT装置では比較的速い洗い出し過程の撮像は困難であった. 今回, 短時間にデータ収集が可能な連続回転収集機能 (リターンモード) を有する3検出器型SPECT装置を用いて, ボランティア (6例) および種々の肺疾患 (23例) を対象に, 133Xeガスの肺洗い出しSPECTを施行し検討した. 133Xe (60〜72 MBq/l) を閉鎖回路内で6分間吸入後の平衡像と引き続き開放回路として洗い出し像を連続的に60秒毎のデータ収集により撮像した. 洗い出しの指標は平衡時の肺局所放射能が半減する時間 (T1/2) を用いた. 健常肺では洗い出しに対する重力効果が把握された. 肺疾患群では拘束性肺疾患を除き全例で, 胸部X線CT像の異常影の有無に関わらず, 洗い出し遅延部が検出され, T1/2も健常例に比し遅延していた. 本検査は局所換気異常の3次元的把握に有用である. |
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| Practice | 臨床医学：一般 |
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| Keywords | SPECT, Lung, Xenon-133, Ventilation, Dynamic study |
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| English |
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| Title | Evaluation of Regional Pulmonary 133Xe-Gas Washout with Dynamic SPECT Imaging Obtained by a Triple-Headed SPECT System with Continuous Repetitive Rotating Acquisition Mode |
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| Authors | Kazuyoshi SUGA, Kazuya NISHIGAUCHI, Norihiko KUME, Katsuyuki TAKANO, Shinji KOIKE, Tsuneo MATSUMOTO, Naofumi MATSUNAGA |
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| Authors(kana) | |
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| Organization | Department of Radiology, Yamaguchi University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 32 |
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| Number | 1 |
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| Page | 51-61 |
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| Year/Month | 1995/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] The clinical potential of the dynamic SPECT in studying pulmonary washout of Xenon-133 (133Xe), using a triple-headed SPECT system (Toshiba GCA 9300A/HG, Japan) with continuous repetitive rotating acquisition mode, was preliminarily investigated in 6 healthy volunteers and 23 patients with various lung diseases. The equilibrium image was initially acquired for 1 min after breathing 133Xe gas (370 MBq) in a closed circuit for 6 min, and subsequently serial 133Xe-washout SPECT images were continuously acquired every 60 sec for 5-6 min. As the ventilation index, the real half time of regional activity was evaluated. The SPECT study demonstrated the gravity-induced gradient on ventilation in the normal subjects. In the various lung diseases, it allowed us to demonstrate visually and quantitatively the dynamic process and three-dimensional distribution of ventilation abnormalities, with or without chest radiographic abnormalities. These results indicate clinical potential of pulmonary dynamic SPECT of 133Xe-washout for elucidating the distribution and nature of ventilation abnormalities in various lung diseases. |
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| Practice | Clinical medicine |
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| Keywords | SPECT, Lung, Xenon-133, Ventilation, Dynamic study |
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