| Japanese |
|---|
| Title | 123I-BMIPPダイナミックSPECTを利用した心筋血流と脂肪酸の同時評価 |
|---|
| Subtitle | 原著 |
|---|
| Authors | 小林秀樹*, 浅野竜太**, 井上征治**, 岡俊明**, 百瀬満**, 一方井裕子**, 住吉徹哉**, 松本延介**, 堀江俊伸**, 日下部きよ子*, 細田瑳一** |
|---|
| Authors(kana) | |
|---|
| Organization | *東京女子医科大学放射線科, **循環器内科 |
|---|
| Journal | 核医学 |
|---|
| Volume | 32 |
|---|
| Number | 1 |
|---|
| Page | 19-29 |
|---|
| Year/Month | 1995/1 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」123I-BMIPP投与直後からダイナミックSPECTを用いて心筋像を撮像し, 123I-BMIPP投与後2〜5分の初期分布像の臨床的意義について検討した. ダイナミックSPECTの撮像は, 3検出器ガンマカメラを用いて123I-BMIPP投与2分後から3分毎に連続5回施行した. 不安定狭心症の10例中8例, 心筋梗塞の11例中9例は, 投与2分後から撮像した123I-BMIPP像が安静時201Tl像ときわめて類似したRI集積所見を呈した. 不安定狭心症の10例全例, 心筋梗塞の11例中5例は, 安静時201Tl像と比べ123I-BMIPP投与30分後像で低集積領域を認めた. 非虚血性心疾患6例は, 投与2分後と30分後に撮像した123I-BMIPP像がいずれも安静時201Tl像と同様の所見を呈した. 以上より, 123I-BMIPP投与後2〜5分で撮像される初期分布像は心筋血流を反映した像が得られている所見であり, 初期分布像と30分後の遅延像を撮像することによって123I-BMIPP 1回の投与で心筋血流と脂肪酸代謝の同時評価ができる可能性が示唆された. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | Beta-methyl-iodophenylpentadecanoic acid (BMIPP), Dynamic SPECT, Myocardial perfusion, Myocardial viability, Unstable angina pectoris |
|---|
| English |
|---|
| Title | Simultaneous Evaluation of Myocardial Perfusion and Fatty Acid Metabolism Using Dynamic SPECT with Single Injection of 123I-15-(p-Iodophenyl)-3-Methyl Pentadecanoic Acid (BMIPP) |
|---|
| Subtitle | Original Articles |
|---|
| Authors | Hideki KOBAYASHI*, Ryuta ASANO**, Toshiaki OKA**, Seiji INOUE**, Mitsuru MOMOSE**, Yuko IKKATAI**, Tetsuya SUMIYOSHI**, Nobusuke MATSUMOTO**, Toshinobu HORIE**, Kiyoko KUSAKABE*, Saichi HOSODA** |
|---|
| Authors(kana) | |
|---|
| Organization | *Department of Radiology, Tokyo Women's Medical College Hospital, **Department of Cardiology, Tokyo Women's Medical College Hospital |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 32 |
|---|
| Number | 1 |
|---|
| Page | 19-29 |
|---|
| Year/Month | 1995/1 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary] The purpose of this study is to clarify whether dynamic SPECT (DECT) immediately after the injection of 123I-15-(p-iodophenyl)-3-methyl pentadecanoic acid (BMIPP) may represent myocardial perfusion imaging. Ten patients with unstable angina pectoris (UAP), 11 patients with acute myocardial infarction (AMI) and 6 patients with non-ischemic heart disease (NIHD) were studied using BMIPP myocardial scintigraphy with DECT. DECT acquisition was started 2 minutes after the injection of BMIPP, and DECT images were obtained every three minute for 15 minutes with 3-headed gamma camera SPECT system. Additionally, static SPECT images were acquired 30 minutes after the injection of BMIPP. These SPECT images of BMIPP were compared with thallium-201 myocardial perfusion images at rest. In UAP group, early DECT images showed almost the same findings as thallium-201 images in 8 of 10 patients, and SPECT images at 30 minutes after the injection showed reduced accumulation of BMIPP compared with thallium-201 images in all patients. In AMI group, early DECT images showed the same findings as thallium-201 perfusion images in 9 of 11 patients, and SPECT images at 30 minutes after the injection showed reduced accumulation of BMIPP compared with thallium-201 images in 5 of 11 patients. These results indicate that myocardial perfusion can be evaluated in the early image using DECT, in addition to myocardial fatty acid metabolism in the delayed image. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | Beta-methyl-iodophenylpentadecanoic acid (BMIPP), Dynamic SPECT, Myocardial perfusion, Myocardial viability, Unstable angina pectoris |
|---|