| Japanese |
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| Title | 体部メチオニンPETにおける至適撮像時期および集積評価法の検討 |
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| Subtitle | 技術報告 |
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| Authors | 佐々木雅之*, 赤司祐子*, 一矢有一*, 桑原康雄*, 吉田毅*, 福村利光*, 増田康治* |
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| Authors(kana) | |
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| Organization | *九州大学医学部放射線科 |
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| Journal | 核医学 |
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| Volume | 31 |
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| Number | 12 |
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| Page | 1547-1552 |
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| Year/Month | 1994/12 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」体部メチオニンPETにおける至適撮像時期の検討および集積評価法である腫瘍筋肉比 (TMR) とDARの比較検討を行った. 対象は腫瘍38例, 炎症4例の計42例である. 病変部のTMRは45〜60分後のTMRに対して, 5分後96±23%, 10〜20分後91±8.6%, 20〜32分後94±6.9%, 32〜40分後96±6.9%であった. 投与後10分以内では漸増するものやピークを形成するものなど症例ごとに異なっていた. 10分以後では一定の増加傾向を示したが, 各時点とも45〜60分後のTMRと良好な相関関係を認めた (r=0.97〜0.99). 一方, 10分以後の各時点でのTMRとDARは, 正常組織, 病変部ともに良好な相関を示した (r=0.89〜0.96). 以上の結果より, 体部メチオニンPETの撮像は投与10分後以降で可能であり, TMRとDARは同様の結果が得られると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Positron emission tomography, 11C-methionine |
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| English |
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| Title | A Useful Method to Evaluate 11C-Methionine Uptake Using Positron Emission Tomography : Determination of the Optimal Scanning Time for Evaluation and a Comparison between the Tumor-to-Muscle Ratio and the Distribution Absorption Ratio |
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| Subtitle | |
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| Authors | Masayuki SASAKI, Yuko AKASHI, Yuichi ICHIYA, Yasuo KUWABARA, Tsuyoshi YOSHIDA, Toshimitsu FUKUMURA, Kouji MASUDA |
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| Authors(kana) | |
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| Organization | Department of Radiology, Faculty of Medicine, Kyushu University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 31 |
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| Number | 12 |
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| Page | 1547-1552 |
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| Year/Month | 1994/12 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] We determined the optimal scanning time for evaluating 11C-methionine uptake and then compared the usefulness of the tumor-to-muscle ratio (TMR) with the distribution absorption ratio (DAR) using positron emission tomography. Forty-two PET studies were performed to examine 42 tumorous lesions, 25 normal lung tissues, 23 normal bone marrow and 39 blood pool. In the 42 lesions examined, the TMR at 5, 10-20, 20-32 and 32-40 minutes after 11C-methionine injection, compared with that at 45-60 minutes, was 96+-23%, 91+-8.6%, 94+-6.9% and 96+-6.9%, respectively. A correlation study between the TMR and the DAR demonstrated good results in both the normal tissue (r=0.96) and the tumorous lesions (r=0.93). In conclusion, the 11C-methionine uptake can be evaluated at any time from 10 minutes after the injection of 11C-methionine and both the TMR and the DAR are considered to be useful methods for evaluating 11C-methionine uptake using positron emission tomography. |
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| Practice | Clinical medicine |
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| Keywords | Positron emission tomography, 11C-methionine |
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