| Japanese |
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| Title | 狭心症患者における安静時123I-BMIPP心筋シンチの臨床的意義 |
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| Subtitle | 原著 |
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| Authors | 塩谷英之*, 上野洋*, 松永公雄* |
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| Authors(kana) | |
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| Organization | *兵庫県立成人病センター内科 |
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| Journal | 核医学 |
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| Volume | 31 |
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| Number | 11 |
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| Page | 1343-1349 |
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| Year/Month | 1994/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」狭心症患者の虚血評価における安静時BMIPP心筋シンチの臨床的意義を明らかにする目的で, 心筋梗塞の既往がなく運動負荷Tl心筋シンチにて一過性灌流欠損が認められた狭心症患者20例を対象に安静時BMIPP心筋シンチを施行した. BMIPP像でのdefectの有無から対象を2群に分類し, 運動負荷時諸指標, 冠動脈所見等を比較した. さらにTl心筋シンチ上の一過性灌流欠損部における左室壁運動をBMIPP像でのdefectの有無で比較検討を行った. BMIPP心筋シンチにて20例中11例にdefectを認め, defectを認めた群は認めなかった群に比し運動時負荷量は低く, 心電図上のST低下は大であり, 冠動脈造影上多枝病変が有意に多かった (64% vs. 12%). Tlの一過性欠損部29区域においてBMIPPにてdefectを示した14区域ではdefectを示さない15区域よりも壁運動異常 (hypokinesis) を伴う頻度が多い傾向があった (82% vs. 33%). [総括] 以上の結果より狭心症患者のうちBMIPP心筋シンチにて異常を示す例は示さない例に比べ, より高度の虚血が存在する可能性が示唆され, BMIPP心筋シンチが虚血の有無の同定よりもむしろ重症度評価に有用であると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-BMIPP, Thallium-201, Angina pectoris, Fatty acid metabolism |
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| English |
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| Title | Myocardial SPECT with Iodine-123-Labeled Beta-Methyl-Branched Fatty Acid in Patients with Angina Pectoris |
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| Subtitle | Original Articles |
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| Authors | Hideyuki SHIOTANI, Hiroshi UENO, Kimio MATSUNAGA |
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| Authors(kana) | |
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| Organization | Department of Cardiology, Hyogo Medical Center for Adults |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 31 |
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| Number | 11 |
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| Page | 1343-1349 |
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| Year/Month | 1994/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] To evaluate the usefulness of 123I-BMIPP as a tracer of fatty acid metabolism in patients with angina pectoris, we performed rest BMIPP myocardial SPECT and stress 201Tl SPECT in 20 patients with angina pectoris. BMIPP SPECT was evaluated in the defected regions with Tl redistribution. Abnormal findings in BMIPP were observed in 11 of 20 patients and in 14 of 29 myocardial segments with Tl redistribution. Such decreased uptake was observed more often in patients with multivessel disease (64% vs. 12%). In addition, the decreased BMIPP uptake was seen more often in the segments exhibiting hypo-kinesis than the segments showing with normal wall motion. Thus, BMIPP imaging may be available to detect myocardial ischemia, particularly in patients with severe coronary disease. |
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| Practice | Clinical medicine |
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| Keywords | 123I-BMIPP, Thallium-201, Angina pectoris, Fatty acid metabolism |
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