| Japanese |
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| Title | 甲状腺腫瘍における99mTc-MIBI甲状腺シンチグラフィの検討 |
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| Subtitle | 原著 |
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| Authors | 小須田茂*, 新井眞二*, 片山通章*, 横山久朗*, 草野正一*, 中之坊学**, 野原理**, 井上鐵三** |
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| Authors(kana) | |
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| Organization | *防衛医科大学校放射線医学講座, **耳鼻咽喉科学講座 |
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| Journal | 核医学 |
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| Volume | 31 |
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| Number | 11 |
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| Page | 1335-1342 |
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| Year/Month | 1994/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」甲状腺腫瘍患者18例に99mTc-MIBIによる甲状腺シンチグラフィを術前に施行し, 従来の甲状腺シンチグラフィと対比した. 甲状腺悪性腫瘍11例 (乳頭癌8, 濾胞癌, 未分化癌, 悪性リンパ腫, 各1) 全例が早期像にて腫瘍に一致して集積増加を示したが, そのうち5例 (45.4%) は遅延像にて洗い出しを示した. 広範囲頸部リンパ節転移の一例では99mTc-MIBIの転移巣への明瞭な集積がみられた. 嚢胞成分主体の甲状腺腺腫4例は欠損像を示したが, 実質成分主体の腺腫3例中2例は早期・遅延像とも強い集積増加を示した. 未分化癌, 悪性リンパ腫の各1例では軽度の集積増加がみられた. 結論として, 甲状腺実質性腫瘍14例全例において, 99mTc-MIBIの集積増加が認められ, 201Tlと比較して同等かやや優れたシンチグラムが得られた. 99mTc-MIBIシンチグラフィは甲状腺腫瘍の良性・悪性の鑑別に用いるには適さないものの, 実質性腫瘍の局在とその転移巣把握に有用であると思われた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-hexakis 2-methoxy isobutyl isonitrile, Thyroid scintigraphy, Thyroid cancer, Thyroid adenoma |
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| English |
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| Title | Thyroid Scintigraphy in Patients with Thyroid Tumors Using 99mTc-Hexakis 2-Methoxy Isobutyl Isonitrile |
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| Subtitle | Original Articles |
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| Authors | Shigeru KOSUDA*, Shinji ARAI*, Michiaki KATAYAMA*, Hisao YOKOYAMA*, Shoichi KUSANO*, Manabu NAKANOBO**, Satoshi NOHARA**, Tetsuzo INOUE** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **Department of Otolaryngology, National Defense Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 31 |
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| Number | 11 |
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| Page | 1335-1342 |
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| Year/Month | 1994/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Early and delayed thyroid scintigraphy with 99mTc-hexakis 2-methoxy isobutyl isonitrile (99mTc-MIBI) was performed in 18 patients with thyroid tumor, including 8 with papillary carcinoma, 1 each with follicular carcinoma, anaplastic carcinoma, and malignant lymphoma, and 7 with thyroid adenoma. Scintigrams obtained were compared with those taken with other radionuclides. In all 11 patients with malignant tumors, increased 99mTc-MIBI uptake was noted in the tumors on early images, although anaplastic carcinoma and malignant lymphoma had mild uptake. On delayed images, 99mTc-MIBI washout was noted in 45.4% (5/11). In one patient with extensive cervical lymph node metastasis, 99mTc-MIBI concentration was evident in the metastatic foci. In the 4 where, the thyroid adenoma consisted mainly of cystic degeneration, a focal defect was noted, but two of the three patients whose thyroid adenoma consisted mainly of a solid component had an intense tracer uptake in the tumors on early and delayed images. In conclusion, there were increased 99mTc-MIBI accumulations in all of the 14 solid thyroid tumors. The quality of 99mTc-MIBI scintigraphic images of thyroid tumors was equal or slightly superior to that taken with 201Tl Scintigraphy. 99mTc-MIBI thyroid scintigraphy may be useful in detecting a solid thyroid tumor and its metastasis, although it cannot be used to differentiate between benign and malignant tumors. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-hexakis 2-methoxy isobutyl isonitrile, Thyroid scintigraphy, Thyroid cancer, Thyroid adenoma |
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