| Japanese |
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| Title | 123I metaiodobenzylguanidine (MIBG) 心筋像への星状神経節ブロックの影響 |
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| Subtitle | 短報 |
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| Authors | 木下信一郎*, 宮前達也**, 松本勲***, 菅井実***, 大日方研**, 鈴木成雄*, 西村克之**, 酒井悠次****, 土肥豊* |
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| Organization | *埼玉医科大学第二内, **放射線科, ***麻酔科, ****薬理学 |
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| Journal | 核医学 |
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| Volume | 31 |
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| Number | 10 |
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| Page | 1249-1253 |
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| Year/Month | 1994/10 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」123I metaiodobenzylguanidine(MIBG)の心筋への取り込みが, 星状神経節ブロック(SGB)により影響を受けるか否かを検討した. 心疾患のない4例で, SGB時, 非SGB時の2回, MIBG静注10分後, 60分後に, planar胸部正面像, SPECT心筋像を撮像した. planar像において, 心臓の取り込みを交感神経支配の異なる肝の取り込みで除した値を, SGB時, 非SGB時で比較すると, 10分後, 60分後ともSGB時で有意に高値であった. 心筋SPECT像では, 非SGB時に比し, SGB時に局所的欠損または取り込み上昇のみられた例はなかった. 以上から, SGBはMIBGの心筋への取り込みを総体的に増加させ, 局所的な取り込みの変化はもたらさないと考えられた. 「I. はじめに」123I metaiodobenzylguanidine(MIBG)による心筋イメージングが広く臨床応用されるようになり, 多くの心疾患でその有用性が報告されている. しかし, MIBG画像の意味は今日なお十分に明らかではなく, 実験的, 臨床的検討が続けられている. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-metaiodobenzylguanidine, Stellate ganglion block, Sympathetic nerve, Heart. |
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| English |
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| Title | The Effect of Stellate Ganglion Block on the Local and Global Cardiac Uptake of 123I-Metaiodobenzylguanidine |
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| Authors | Shinichiro KINOSHITA*, Tatsuya MIYAMAE**, Tsutomu MATSUMOTO***, Minoru SUGAI***, Ken OBINATA**, Shigeo SUZUKI*, Katsuyuki NISHIMURA**, Yuuji SAKAI****, Yutaka DOHI* |
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| Authors(kana) | |
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| Organization | *Second Department of Internal Medicine, Saitama Medical School, **Department of Radiology, Saitama Medical School, ***Department of Anesthesia, Saitama Medical School, ****Department of Pharmacology, Saitama Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 31 |
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| Number | 10 |
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| Page | 1249-1253 |
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| Year/Month | 1994/10 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] To investigate the effect of stellate ganglion block (SGB) on the cardiac uptake of 123I-metaiodobenzylguanidine (MIBG), four patients without heart disease underwent SGB. Studies were done twice: once with SGB and once without SGB. Anterior planar images and myocardial SPECT images were taken at 10 minutes and 60 minutes after MIBG injection both with and without SGB. Cardiac uptake of MIBG on planar images estimated by heart/liver ratio was significantly higher with SGB at both imaging times (p<0.01, p<0.05) than without SGB. SGB had no effect on the local uptake of MIBG on SPECT images. In conclusion, SGB did not change the local cardiac uptake of MIBG, but it appeared to increase the global myocardial uptake of MIBG. |
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| Practice | Clinical medicine |
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| Keywords | 123I-metaiodobenzylguanidine, Stellate ganglion block, Sympathetic nerve, Heart. |
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