| Japanese |
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| Title | 81mKrガス, 99mTc-MAAの2核種同時収集 SPECTによる肺換気 / 血流比の検討 |
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| Subtitle | 原著 |
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| Authors | 山洞善恒* |
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| Authors(kana) | |
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| Organization | *群馬大学医学部第二内科 |
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| Journal | 核医学 |
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| Volume | 31 |
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| Number | 10 |
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| Page | 1209-1218 |
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| Year/Month | 1994/10 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」81mKrガスと99mTc-MAAの2核種同時収集肺SPECTより換気/血流比の機能画像を作成し, 仰臥位における換気/血流比分布を評価した. さらに, 換気/血流比ヒストグラムの重心(CW)と標準偏差(SD)を用いて換気血流不均等分布の客観的評価を試みた. 正常例では, 換気/血流比は背側で低く腹側で高かった. 肺血管病変例では, 大葉性や楔形の高換気/血流比領域を認めた. 肺気腫例では, 広範な低換気/血流比領域に斑状の高換気/血流比領域が混在していた. CWは肺気腫例で低下し, SDは肺血管病変例, 肺気腫例で増大していた. CWの上昇はミスマッチ主体の, 低下はリバースミスマッチ主体の換気血流不均等分布を示唆すると考えられた. SDはPA-aO2と相関係数r=0.775の強い正の相関を示し, SDにより換気血流不均等分布の定量化が可能と考えられる. |
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| Practice | 臨床医学：一般 |
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| Keywords | Ventilation/perfusion ratio, Dual radionuclides SPECT, Functional image. |
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| English |
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| Title | Assessment of Pulmonary Ventilation / Perfusion Ratio by Dual Radionuclides SPECT Using 81mKr Gas and 99mTc-MAA |
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| Subtitle | |
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| Authors | Yoshichika SANDO |
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| Authors(kana) | |
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| Organization | Second Department of Internal Medicine, Gunma University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 31 |
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| Number | 10 |
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| Page | 1209-1218 |
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| Year/Month | 1994/10 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] The accuracy and clinical availability of pulmonary ventilation/perfusion (V/Q) ratio images by 81mKr gas and 99mTc-MAA dual radionuclides SPECT was assessed in 10 normal volunteers and 31 patients with pulmonary diseases. After equalizing the total acquisition counts of both radionuclides, the ratio of 81mKr/99mTc count was calculated in each pixel and expressed as the functional map of V/Q. Then, the histogram of pixel numbers against V/Q ratio was drawn and the center of weight (CW) and standard deviation (SD) of the distribution were determined. The reproducibility of this method was excellent. In normal volunteers, CW was 1.07 and the SD was 0.25. The V/Q was lower in dorsal than in the ventral portion. SD was large and lobar or segmental high V/Q areas were clearly noted in the patients with pulmonary vascular diseases. In pulmonary emphysema, large low V/Q areas coexisted with patchy high V/Q areas. CW was small and SD was large in this group. There was a significant positive correlation between SD and PA-aO2. The author believes that the pulmonary ventilation/perfusion (V/Q) ratio images by dual radionuclides SPECT is a useful diagnostic procedure. Further, SD determined by this examination is thought to be a good parameter of uneven distribution of pulmonary ventilation and perfusion. |
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| Practice | Clinical medicine |
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| Keywords | Ventilation/perfusion ratio, Dual radionuclides SPECT, Functional image. |
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