| Japanese |
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| Title | 慢性内頸動脈閉塞例における脳血管造影による局所脳循環時間とPETによる局所脳循環代謝諸量との対比 |
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| Subtitle | 原著 |
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| Authors | 伊藤浩*,***, 犬上篤*, 宍戸文男*, 奥寺利男*, 小川敏英*, 畑澤順*, 藤田英明*, 下瀬川恵久*, 菅野巖*, 福田寛***, 上村和夫* |
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| Authors(kana) | |
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| Organization | *秋田県立脳血管研究センター放射線科, **福島県立医科大学放射線科, ***東北大学加齢医学研究所加齢脳神経部門 機能画像医学研究分野 |
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| Journal | 核医学 |
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| Volume | 31 |
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| Number | 10 |
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| Page | 1193-1199 |
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| Year/Month | 1994/10 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」慢性内頸動脈閉塞例における側副血行路の程度を脳血管造影上の造影剤の平均通過時間により評価し, PETによる局所脳循環代謝諸量(脳血流量(CBF), 脳酸素摂取率(OEF), 脳酸素代謝率(CMRO2), 脳血液量(CBV))と比較した, 脳血管造影上の平均通過時間はCBFと有意の負の相関を, OEFとは有意の正相関を示し, 脳血管造影上の造影剤の平均通過時間より脳循環代謝諸量がある程度推定できることが示唆された. また, CMRO2は脳血管造影上の平均通過時間にかかわらずほぼ一定に保たれていた. 脳血管造影上の平均通過時間とPETによる脳血流の平均通過時間(CBV/CBF)との間には有意な相関はみとめられなかった. 脳血管造影上の平均通過時間を各相別に分けると, 静脈相においてのみCBFとの間に有意の負の相関をみとめたが, 静脈相の平均通過時間が血圧に依存することから, 慢性内頸動脈閉塞例におけるCBF低下の主因は灌流圧の低下である可能性が示唆された. |
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| Practice | 臨床医学：一般 |
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| Keywords | PET, CBF, Angiography, Circulation time, ICA occlusion. |
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| English |
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| Title | Circulation Time Determined by Carotid Angiography in Patients with Chronic Internal Carotid Artery Occlusion : Comparison with Cerebral Blood Flow and Oxygen Metabolism Measured by PET |
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| Subtitle | Original Articles |
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| Authors | Hiroshi ITo*,***, Atsushi INUGAMI*, Fumio SHISHIDO**, Toshio OKUDERA*, Toshihide OGAWA*, Jun HATAZAWA*, Hideaki FUJITA*, Eku SHIMOSEGAWA*, Iwao KANNO*, Hiroshi FUKUDA***, Kazuo UEMURA* |
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| Authors(kana) | |
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| Organization | *Department of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels, **Department of Radiology and Nuclear Medicine, Fukushima Medical College, ***Department of Nuclear Medicine and Radiology, Division of Brain Sciences, Institute of Development, Aging and Cancer, Tohoku University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 31 |
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| Number | 10 |
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| Page | 1193-1199 |
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| Year/Month | 1994/10 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] The degree of collateral circulation in patients with unilaterally chronic internal carotid artery occlusion was estimated by mean transit time of contrast material in rapid sequence carotid angiography (Angiographic MTT), and compared with cerebral blood flow and oxygen metabolism measured by PET. In normal density region on X-ray CT, a significant negative correlation was observed between Angiographic MTT and cerebral blood flow (CBF). This indicates that cerebral blood flow can be estimated by Angiographic MTT. It has been reported that the ratio of cerebral blood volume (CBV) to CBF (CBV/CBF), i.e., mean transit time determined by PET well agreed with OEF, and is good indicator for brain circulation reserve. In this study, no significant correlation was observed between Angiographic MTT and CBV/CBF. However, a significant positive correlation was observed between Angiographic MTT and oxygen extraction fraction (OEF), and no significant correlation was observed between Angiographic MTT and oxygen consumption rate (CMRO2). These indicates that Angiographic MTT may be indicator for brain circulation reserve. |
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| Practice | Clinical medicine |
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| Keywords | PET, CBF, Angiography, Circulation time, ICA occlusion |
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