Japanese
TitleCircumferential Profile Analysisによる123I-BMIPPと201TlCl心筋イメージングの比較 - 心筋梗塞患者の血行再建の評価 -
Subtitle原著
Authors大角幸男*, 渡辺正*, 長野俊彦*
Authors(kana)
Organization*羽島市民病院内科
Journal核医学
Volume31
Number10
Page1167-1175
Year/Month1994/10
Article原著
Publisher日本核医学会
Abstract「要旨」心筋梗塞患者を対象とし, 血行再建術の施行時期による効果を評価するために123I-BMIPPと201TlClを別々に使用し, circumferential profile(CP)curve法にて定量的に検討した. (1)健常者(n=9)の2核種のCP curveを比較したところ分布に差を認めなかった. (2)心筋梗塞患者(n=32)において健常者から作成したCP curveを用いて"severity score"により評価した. その結果, 急性期に血行再建が成功した群(I)と慢性期の血行再建成功群(II)では, それぞれ83%, 91%とB型(123I-BMIPPの集積低下大)が多く, 血行再建不成功と未施行群(III)ではE型(2核種の集積低下ほぼ等しい)が74%と多かった. 2核種とも"severity score"では, I群とIIおよびIII群との間に有意差を認めず, 123I-BMIPP score/201TlCl score比はII>I>IIIの順に大であった(p<0.05). 2核種の"severity score"の比を検討することが生存心筋の評価に有用であると考えられた.
Practice臨床医学:一般
Keywordsβ-methyl-p-iodophenyl-pentadecanoic acid (123I-BMIPP), 201TlCl, Myocardial infarction, SPECT, Circumferential profile analysis.
English
TitleComparison between 123I-BMIPP and 201TlCl Myocardial Imaging by Circumferential Profile Analysis in Patients with Myocardial Infarction - Evaluation of Effects of Vascular Reconstruction in Patients with Myocardial Infarction -
SubtitleOriginal Articles
AuthorsYukio OHSUMI, Tadashi WATANABE, Toshihiko NAGANO
Authors(kana)
OrganizationDepartment of Medicine, Hashima City Hospital
JournalThe Japanese Journal of nuclear medicine
Volume31
Number10
Page1167-1175
Year/Month1994/10
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] We quantitatively evaluated the effects of vascular reconstruction according to the stage by 123I-BMIPP and 201TlCl using circumferential profile (CP) curve method in patients with myocardial infarction. (1) Comparison of the CP curves for the two nuclides in normal volunteers (n=9) showed no difference in distribution. (2) In patient with myocardial infarction (n=32) the severity score was evaluated using the CP curves obtained in the normal volunteers. Type B (marked decrease in 123I-BMIPP accumulation) accounted for 83% in the group in whom vascular reconstruction was performed in the acute stage (Group I) and 91% in the group in whom vascular reconstruction was performed in the chronic stage (Group II). On the other hand, type E (similar accumulation between the two nuclides) accounted for 79% in the group in whom vascular reconstruction was unsuccessful or was not performed (Group III). The severity score for each nuclide did not significantly differ among Group I, II and III. The 123I-BMIPP/201TlCl ratio was the highest in Group II, followed in order by Group I and Group III (p<0.05). The assessment of the ratio of "severity scores" for both nuclides is considered to be useful for evaluation of the surviving myocardium, rather than the assessment of a single nuclide.
PracticeClinical medicine
Keywordsβ-methyl-p-iodophenyl-pentadecanoic acid (123I-BMIPP), 201TlCl, Myocardial infarction, SPECT, Circumferential profile analysis.

【全文PDF】