| Japanese |
|---|
| Title | 側頭葉てんかん患者の123I-IMP SPECT, 脳波, MRIの比較検討 |
|---|
| Subtitle | 原著 |
|---|
| Authors | 辰吉光*, 西垣洋*, 足立至*, 松岡孝枝*, 芦名謙介*, 平石久美子*, 松井律夫*, 末吉公三*, 楢林勇*, 左光治**, 堺俊明*** |
|---|
| Authors(kana) | |
|---|
| Organization | *大阪医科大学放射線医学教室, **中央検査部, ***神経精神医学教室 |
|---|
| Journal | 核医学 |
|---|
| Volume | 31 |
|---|
| Number | 9 |
|---|
| Page | 1077-1084 |
|---|
| Year/Month | 1994/9 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」側頭葉てんかん患者19人のelectroencephalography(EEG), MRI, N-isopropyl-p[123I]iodoamphetamine(123I-IMP)single photon emission computed tomography(SPECT)を比較検討した. EEGにおいては経過観察中に全例側頭部に異常波を認めた. MRIでは19例中10例に異常を認め, 全例側頭葉内側海馬部の異常であった. 123I-IMP SPECTでは19例中15例に側頭葉内側海馬部に血流低下を指摘できた. 脳波の異常側と比較すると, MRIでは10例中3例に, 123I-IMP SPECTでは15例中6例で異常側に乖離が見られたが, MRIと123I-IMP SPECTに乖離は見られなかった. 123I-IMP SPECT像における再構成方向における検討では, axial像よりcoronal像および海馬に平行な断層像の方が異常検出率が高く, 後者では長軸方向の血流低下範囲が明瞭に描出できた. 発作との関係では発作後時間が経過していない症例において, 123I-IMP SPECTにおける血流低下範囲は, MRIにおける異常範囲より広範囲になる傾向が認められた. 海馬に平行な断層像は, 側頭葉てんかん患者の血流低下範囲を知る上で有用であった. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | Temporal lobe epilepsy, 123I-IMP SPECT, MRI, Electroencephalography. |
|---|
| English |
|---|
| Title | A Comparison among 123I-IMP SPECT, EEG and MRI in Patients with Temporal Lobe Epilepsy |
|---|
| Subtitle | |
|---|
| Authors | Yoshimitsu TATSU*, Hiroshi NISHIGAKI*, Itaru ADACHI*, Takae MATSUOKA*, Kensuke ASHINA*, Kumiko HIRAISHI*, Ritsuo MATSUI*, Kouzou SUEYOSHI*, Isamu NARABAYASHI*, Mitsuharu HIDARI**, Toshiaki SAKAI* |
|---|
| Authors(kana) | |
|---|
| Organization | *Department of Radiology, Osaka Medical College, **Department of Laboratory Medicine, Osaka Medical College, ***Department of Neuropsychiatry, Osaka Medical College |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 31 |
|---|
| Number | 9 |
|---|
| Page | 1077-1084 |
|---|
| Year/Month | 1994/9 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary] N-isopropyl-p[123I]iodoamphetamine (123I-IMP) single photon emission computed tomography (SPECT), electroencephalography (EEG), and magnetic resonance imaging (MRI) were performed in 19 patients with temporal lobe epilepsy during interictal stage. MRI demonstrated abnormal signal in mesial temporal lobe (hippocampus) in 10 of 19 patients and 123I-IMP SPECT showed a hypoperfusion area in 15 of 19 patients. When compared with EEG and MRI data, disagreement of the affected area was observed in 3 cases. In comparison of EEG and 123I-IMP SPECT data, disagreement of the affected area was observed in 6 cases. Although there were no disagreement in comparison of MRI and 123I-IMP SPECT. We made a reprojection data parallel to the hippocampus in 123I-IMP SPECT. These data demonstrated obviously a hypoperfusion area around the hippocampus. In cases within one month from seizure attack, wide hypoperfusion area was showed on 123I-IMP SPECT in comparison of abnormal signal area on MRI. It could be considered that a reprojection data parallel to the hippocampus was useful to know extent of hypoperfusion area in temporal lobe epilepsy. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | Temporal lobe epilepsy, 123I-IMP SPECT, MRI, Electroencephalography. |
|---|