| Japanese |
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| Title | 心筋梗塞症における心筋灌流および壁運動の経時的観察 - 201Tl心筋SPECTならびに99mTc-HSAD心電図同期心プール断層法による検討 - |
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| Subtitle | 原著 |
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| Authors | 南條修二* |
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| Authors(kana) | |
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| Organization | *東邦大学医学部内科学第一講座 |
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| Journal | 核医学 |
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| Volume | 31 |
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| Number | 9 |
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| Page | 1027-1037 |
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| Year/Month | 1994/9 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」急性心筋梗塞(AMI)12例および陳旧性心筋梗塞(OMI)17例に対して99mTc-HSADを用いた心電図同期心プール断層法(心プールSPECT)と201Tl心筋SPECT(Tl)を施行し, 局所壁運動と心筋灌流の関係を比較するとともにAMI症例で治療による経時的変化を検討した. AMI症例は血栓溶解療法を施行した6例を1群, 血栓溶解療法後, 待機的PTCAを施行した6例をII群, OMI症例をIII群とした. III群において心プールSPECTより得られた長軸断層(VLA)における収縮変化率(%LS)と%Tl uptake(%TU)の間にr=0.820と有意(p<0.001)な相関関係が認められた. またakinesia領域の%TUは平均35%未満で, severe hypokinesia領域の48%と比較して低値を示した, AMI症例では急性期および慢性期に心プールSPECTとTl検査を施行したが, akinesia領域では%TUの変化に比べ, %LSはI群で30%, II群は49%に改善し, 早期治療により壁運動が著明に改善した. AMIおよびOMI症例での%TUがそれぞれ50%, 40%以上の領域では心筋viabilityの存在が示唆され, 治療効果を心筋viabilityの観点から評価する上でTlならびに心プールSPECTの併用は有用であった. |
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| Practice | 臨床医学：一般 |
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| Keywords | Cardiac pool SPECT, 99mTc-HSAD, 201Tl myocardial SPECT, Myocardial viability. |
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| English |
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| Title | Evaluation of Left Ventricular Perfusion and Regional Wall Motion in Myocardial Infarction : Using 201Tl Myocardial SPECT and 99mTc-HSAD Multigated Cardiac Blood Pool Emission Computed Tomography |
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| Subtitle | Original Articles |
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| Authors | Shuji NANJYO |
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| Authors(kana) | |
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| Organization | First Department of Internal Medicine, Toho University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 31 |
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| Number | 9 |
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| Page | 1027-1037 |
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| Year/Month | 1994/9 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] In order to evaluate left ventricular regional wall motion and regional myocardial perfusion, 99mTc-HSAD multigated cardiac blood pool emission computed tomography (cardiac pool SPECT) and 201Tl myocardial SPECT (Tl) were performed on 12 patients with acute myocardial infarction (AMI), 6 patients had treated with only thrombolysis in group I and 6 patients had treated with thrombolysis and selective PTCA in group II, 17 patients with old myocardial infarction (OMI) in group III and 5 normal volunteers (controls). The relationship between left ventricular regional wall motion and regional myocardial perfusion was estimated. The relationship between %length shortening (%LS) by cardiac pool SPECT and %. Tl uptake (%TU) was good (r=0.820) in group III. The value for %TU in the segments of akinesia was low (35%) and in the those of severe hypokinesia was higher (48%). In all phases, two groups showed significant relationships between %LS and %TU in group I and II. The %TU was unchanged in the akinetic segment, the %LS changed 30% in group I and the %LS changed to 49% in group II If the %TU is more than 50% (AMI) or 40% (OMI), we would observe viable muscle. The combination of TI and cardiac pool SPECT are useful for evaluating myocardial viability in the patients with AMI. |
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| Practice | Clinical medicine |
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| Keywords | Cardiac pool SPECT, 99mTc-HSAD, 201Tl myocardial SPECT, Myocardial viability. |
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