Japanese
Title心筋梗塞症における心筋灌流および壁運動の経時的観察 - 201Tl心筋SPECTならびに99mTc-HSAD心電図同期心プール断層法による検討 -
Subtitle原著
Authors南條修二*
Authors(kana)
Organization*東邦大学医学部内科学第一講座
Journal核医学
Volume31
Number9
Page1027-1037
Year/Month1994/9
Article原著
Publisher日本核医学会
Abstract「要旨」急性心筋梗塞(AMI)12例および陳旧性心筋梗塞(OMI)17例に対して99mTc-HSADを用いた心電図同期心プール断層法(心プールSPECT)と201Tl心筋SPECT(Tl)を施行し, 局所壁運動と心筋灌流の関係を比較するとともにAMI症例で治療による経時的変化を検討した. AMI症例は血栓溶解療法を施行した6例を1群, 血栓溶解療法後, 待機的PTCAを施行した6例をII群, OMI症例をIII群とした. III群において心プールSPECTより得られた長軸断層(VLA)における収縮変化率(%LS)と%Tl uptake(%TU)の間にr=0.820と有意(p<0.001)な相関関係が認められた. またakinesia領域の%TUは平均35%未満で, severe hypokinesia領域の48%と比較して低値を示した, AMI症例では急性期および慢性期に心プールSPECTとTl検査を施行したが, akinesia領域では%TUの変化に比べ, %LSはI群で30%, II群は49%に改善し, 早期治療により壁運動が著明に改善した. AMIおよびOMI症例での%TUがそれぞれ50%, 40%以上の領域では心筋viabilityの存在が示唆され, 治療効果を心筋viabilityの観点から評価する上でTlならびに心プールSPECTの併用は有用であった.
Practice臨床医学:一般
KeywordsCardiac pool SPECT, 99mTc-HSAD, 201Tl myocardial SPECT, Myocardial viability.
English
TitleEvaluation of Left Ventricular Perfusion and Regional Wall Motion in Myocardial Infarction : Using 201Tl Myocardial SPECT and 99mTc-HSAD Multigated Cardiac Blood Pool Emission Computed Tomography
SubtitleOriginal Articles
AuthorsShuji NANJYO
Authors(kana)
OrganizationFirst Department of Internal Medicine, Toho University School of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume31
Number9
Page1027-1037
Year/Month1994/9
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] In order to evaluate left ventricular regional wall motion and regional myocardial perfusion, 99mTc-HSAD multigated cardiac blood pool emission computed tomography (cardiac pool SPECT) and 201Tl myocardial SPECT (Tl) were performed on 12 patients with acute myocardial infarction (AMI), 6 patients had treated with only thrombolysis in group I and 6 patients had treated with thrombolysis and selective PTCA in group II, 17 patients with old myocardial infarction (OMI) in group III and 5 normal volunteers (controls). The relationship between left ventricular regional wall motion and regional myocardial perfusion was estimated. The relationship between %length shortening (%LS) by cardiac pool SPECT and %. Tl uptake (%TU) was good (r=0.820) in group III. The value for %TU in the segments of akinesia was low (35%) and in the those of severe hypokinesia was higher (48%). In all phases, two groups showed significant relationships between %LS and %TU in group I and II. The %TU was unchanged in the akinetic segment, the %LS changed 30% in group I and the %LS changed to 49% in group II If the %TU is more than 50% (AMI) or 40% (OMI), we would observe viable muscle. The combination of TI and cardiac pool SPECT are useful for evaluating myocardial viability in the patients with AMI.
PracticeClinical medicine
KeywordsCardiac pool SPECT, 99mTc-HSAD, 201Tl myocardial SPECT, Myocardial viability.

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