Japanese
Titleアデノシン三リン酸二ナトリウム (ATP) 負荷タリウム心筋シンチグラフィと運動負荷タリウム心筋シンチグラフィの冠動脈病変診断能の比較
Subtitle原著
Authors鈴木成雄*
Authors(kana)
Organization*埼玉医科大学第二内科
Journal核医学
Volume31
Number8
Page957-967
Year/Month1994/8
Article原著
Publisher日本核医学会
Abstract「要旨」虚血性心疾患患者33名を対象とし, ATP負荷タリウム心筋シンチグラフィによる欠損範囲および欠損程度が, 運動負荷タリウム心筋シンチグラフィのそれと同程度か否かを比較検討した. ATPは, 体重1kg当たり1分間, 0.16mgないし0.18mgを5分間投与した. 運動負荷は, トレッドミルによった. 判定は心筋SPECT像で5区域心筋分割法および4段階表示法による視覚的スコア化を行い, 両負荷法での%Defect indexを求めて対比した. 欠損範囲は, ATP負荷タリウム心筋シンチグラフィ対運動負荷タリウム心筋シンチグラフィそれぞれ初期像51.5%対44.2%, 遅延像36.4%対33.9%, 欠損程度はそれぞれ初期像35.8%対32.3%, 遅延像20.8%対17.2%であった(p=NS). 結論的にATP負荷タリウム心筋シンチグラフィの冠動脈病変診断能は, 運動負荷タリウム心筋シンチグラフィのそれと同等であった.
Practice臨床医学:一般
KeywordsCoronary artery disease, ATP, Thallium scintigraphy, SPECT, Diagnosis.
English
TitleComparison of Diagnostic Value of Coronary Artery Disease between ATP-Stress and Exercise-Stress Thallium Myocardial SPECT Images
Subtitle
AuthorsShigeo SUZUKI
Authors(kana)
OrganizationSecond Department of Internal Medicine, Saitama Medical School
JournalThe Japanese Journal of nuclear medicine
Volume31
Number8
Page957-967
Year/Month1994/8
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] A study was made between adenosine triphosphate disodium (ATP)-stress thallium myocardial scintigrams and exercise-stress scintigrams to compare their respective extents and degree of defects. The subjects of the study were 33 ischemic heart disease patients, who received ATP stress and treadmill exercise stress with a mean interval of 25 days. ATP was infused for 5 minutes with an infusion rate of 0.16 or 0.18mg per kg of body weight per minute. Thallium was injected three minutes after infusion. The percent-defect index (percentage of the extent and degree of the defects for all 33 patients), was calculated with visual scoring using a five-zone myocardial division method and semi-quantitative four-grade representation method for both the ATP and exercise SPECT images. The extent of the defects in ATP and exercise-stress images was 51.5% and 44.2%, and that in redistribution images was 36.4% and 33.9%, respectively. The degree of defects in ATP and exercise-stress images was 35.8% and 32.3%, while that in redistribution images was 20.8% and 17.2%, respectively (p=NS in all cases). In conclusion, the image quality of thallium SPECT with ATP stress was equivalent to that of exercise stress, indicating identical diagnostic values for coronary lesions.
PracticeClinical medicine
KeywordsCoronary artery disease, ATP, Thallium scintigraphy, SPECT, Diagnosis.

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