| Japanese |
|---|
| Title | 経皮的冠動脈形成術前後の心筋血流と心機能の経時的推移 - 運動負荷201Tl心筋断層像, 運動負荷 99mTc心プールシンチグラフィによる検討 |
|---|
| Subtitle | 原著 |
|---|
| Authors | 久保田幸夫*, 村田和彦** |
|---|
| Authors(kana) | |
|---|
| Organization | *群馬大学医学部第二内科学教室, **主任:教授 |
|---|
| Journal | 核医学 |
|---|
| Volume | 31 |
|---|
| Number | 8 |
|---|
| Page | 909-919 |
|---|
| Year/Month | 1994/8 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」経皮的冠動脈形成術(PTCA)施行前後において運動負荷201Tl心筋断層像(Tl-SEPCT)の負荷時心筋灌流低下所見と運動負荷時の局所壁運動との関連を経時的に検討した. PTCAに成功した労作性狭心症で3か月後の評価で再狭窄のない25例を対象とした. PTCA施行前, 施行3-7日後, 3か月後に, Tl-SPECTと運動負荷99mTc心プールシンチグラフィ(RNVG)を施行した. Tl-SPECT上, PTCA施行前では全例で負荷時心筋灌流低下を認め, PTCA 3-7日後では14例で負荷時心筋灌流正常となったが, 11例では負荷時心筋灌流低下を認めた. 3ヵ月後には全例で負荷時心筋灌流低下は消失した. 一方, PTCA 3-7日後では, 負荷時心筋灌流正常, 負荷時心筋灌流低下に関わらず全例で運動負荷時の局所壁運動異常が消失していた. 心筋灌流正常群, 心筋灌流低下群との間に, 臨床所見, 術前の冠狭窄度, hibernationの有無について差は認められなかった. 以上より, PTCA後早期における運動負荷時の血流異常は局所壁運動異常を伴わず, PTCA後早期の負荷時心筋灌流低下所見は臨床上意味のある心筋虚血や再狭窄を意味しないと結論した. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | Percutaneous transluminal coronary angioplasty, Coronary artery disease, Stress thallium-201 myocardial perfusion image, Stress radionuclide ventriculography. |
|---|
| English |
|---|
| Title | Serial Changes in Myocardial Perfusion and Function after Successful Percutaneous Transluminal Coronary Angioplasty, Examined by Stress Thallium-201 Myocardial Scintigraphic and Stress Radionuclide Ventriculographic Studies |
|---|
| Subtitle | Original Articles |
|---|
| Authors | Sachio KUBOTA |
|---|
| Authors(kana) | |
|---|
| Organization | Second Department of Internal Medicine, Gunma University School of Medicine |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 31 |
|---|
| Number | 8 |
|---|
| Page | 909-919 |
|---|
| Year/Month | 1994/8 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary] In order to study the early and late effects of percutaneous transluminal coronary angioplasty (PTCA), 201Tl myocardial perfusion scintigraphy and exercise 99mTc ventriculography were performed in 25 patients who successfully received PTCA. Before PTCA, reduced myocardial perfusion on stress 201Tl image was observed in all 25 patients, while abnormal regional wall motion during exercise was seen in 22 cases. On stress 201Tl images, reduced myocardial perfusion was demonstrated in 11 cases at 3-7 days after PTCA, but in none at 3 months after the procedure. On the other hand, abnormal exercise regional wall motion was not observed in any case after successful PTCA even in the early phase. When the patients were divided into two groups according to the presence or absence of perfusion abnormalities on stress 201Tl images in the early post-PTCA phase, no difference was seen in clinical and coronary angiographic findings, exercise tolerance, 201Tl uptake score, wall motion score or left ventricular ejection fraction before the procedure. Thus, abnormal myocardial perfusion without impairment of regional left ventricular wall motion is frequently seen in the early post-PTCA phase. But this finding does not necessarily indicate associated myocardial ischemia. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | Percutaneous transluminal coronary angioplasty, Coronary artery disease, Stress thallium-201 myocardial perfusion image, Stress radionuclide ventriculography. |
|---|