| Japanese |
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| Title | 虚血性心疾患における運動負荷後局所壁運動異常の改善様式の検討 - 201Tl心筋dynamic SPECTを用いて - |
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| Subtitle | 原著 |
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| Authors | 石黒聡* |
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| Authors(kana) | |
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| Organization | *東邦大学医学部内科学第一講座 |
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| Journal | 核医学 |
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| Volume | 31 |
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| Number | 6 |
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| Page | 593-601 |
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| Year/Month | 1994/6 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」虚血性心疾患の運動負荷後の回復過程における虚血状態からの改善様式, 特に局所壁運動異常の遷延する機序を運動負荷201Tl心筋dynamic SPECT(dynamic SPECT)を用いて検討した. 対象は虚血性心疾患23例で, 全例に対し冠動脈造影, 運動負荷断層心エコー図(ESE), dynamic SPECTを施行した. dynamic SPECTは201TlCl(Tl)静注5分後より3検出器型装置で連続33分間撮像し, 20, 29, 38分後のearly washout rate (early WR), 240分後のdelayed WRを算出した, 得られたESE所見より20分以上局所壁運動異常の遷延したA群8例と, 20分未満で安静時の状態に復したB群15例に分類した. early WRは各時間で, control群(健常例5例), B群に比しA群で有意(p<0.01)に低値を示した. またA群の全例で20分後のearly WRは負の値を示した. 以上より, 局所壁運動異常の遷延する機序の一因として相対的, 持続的心筋灌流低下の関与している可能性が示唆された. |
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| Practice | 臨床医学：一般 |
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| Keywords | Ischemic heart disease, Prolonged wall motion abnormalities, 201Tl myocardial dynamic SPECT, Early washout rate, Exercise stress echocardiography. |
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| English |
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| Title | Aspects of Recovery from Regional Wall Motion Abnormalities after Exercise in Patients with Ischemic Heart Disease Using 201Tl Myocardial Dynamic SPECT |
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| Subtitle | Original Articles |
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| Authors | Satoshi ISHIGURO |
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| Authors(kana) | |
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| Organization | First Department of Internal Medicine, Toho University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 31 |
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| Number | 6 |
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| Page | 593-601 |
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| Year/Month | 1994/6 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Using 201Tl myocardial dynamic SPECT (dynamic SPECT), we studied various aspects of the recovery from exercise-induced ischemia, particularly the mechanism of delayed recovery from wall motion abnormality. The subjects were 23 patients with ischemic heart disease who underwent coronary angiography, exercise stress two-dimensional echocardiography (ESE), and dynamic SPECT. Using a 3-head SPECT system, dynamic SPECT was performed for 33 min consecutively from 5 min after the intravenous injection of 201TlCl (Tl). The regional early washout rate (early WR) was determined at 20, 29, and 38 min after Tl injection, and the delayed washout rate (delayed WR) was determined at 240 min. From the duration of regional wall motion abnormalities on ESE, the patients were divided into Group A (wall motion abnormalities persisting for >=20min, n=8) and Group B (<20 min, n=15). At each point of assessment, early WR was significantly lower in Group A than in the control group (5 healthy subjects) and Group B (p<0.01). In addition, the early WR at 20 min was negative in all Group A patients. The present study suggests that a persistent relative and reduction in myocardial blood flow is one factor responsible for prolonged abnormal regional wall motion. |
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| Practice | Clinical medicine |
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| Keywords | Ischemic heart disease, Prolonged wall motion abnormalities, 201Tl myocardial dynamic SPECT, Early washout rate, Exercise stress echocardiography. |
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