Japanese
Title99mTc-HMPAOを用いた脳血流量の半定量的指標の簡便な算出法
Subtitle原著
Authors宮崎吉春*, 絹谷清剛**, 利波紀久**
Authors(kana)
Organization*公立能登総合病院中央放射線部, **金沢大学医学部核医学教室
Journal核医学
Volume31
Number6
Page551-558
Year/Month1994/6
Article原著
Publisher日本核医学会
Abstract「要旨」99mTc-HMPAOシンチグラフィを用い, 脳血流量の目安となり非侵襲的に得られる新しい指標(brain uptake ratio, BUR)を考案し, 松田らが報告した指標(brain perfusion index, BPI)と比較した. 104例の左右大脳半球208部位において, 99mTc-HMPAO静注後の大動脈弓部の放射能通過量に対する脳内集積率をBURとして算出し, BPIと比較したところ, BURはBPIと有意の相関を示した(r=0.965, p<0.01). SPECT画像のデータを用いることにより, 深部あるいは後頭部の情報もBURによく反映された. BURは小視野ガンマカメラでも算出可能であり, 脳血流量を半定量化する指標として簡便かつ有用と考えられる.
Practice臨床医学:一般
Keywords99mTc-HMPAO, Cerebral blood flow, RI angiography, SPECT, Brain uptake ratio.
English
TitleA Simple Method to Obtain Semi-quantitative Index of Brain Perfusion Using 99mTc-HMPAO
SubtitleOriginal Articles
AuthorsYoshiharu MIYAZAKI*, Seigo KINUYA**, Norihisa TONAMI**
Authors(kana)
Organization*Section of Nuclear Medicine, Noto General Hospital, **Department of Nuclear Medicine, School of Medicine, Kanazawa University
JournalThe Japanese Journal of nuclear medicine
Volume31
Number6
Page551-558
Year/Month1994/6
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] We developed a new noninvasive index (brain uptake ratio, BUR) inferring brain perfusion using 99mTc-HMPAO scintigraphy, and compared with the index (brain perfusion index, BPI) reported by Matsuda, et al. BUR was obtained for 208 cerebral hemispheres from 104 cases as a ratio of radioactivity in a brain against that passing through an aortic arch. BUR correlated well with BPI (r=0.965, p<0.01). Information in deep or occipital regions was reflected well to BUR when data of SPECT images were used. BUR can be obtained even with a small field-of-view gamma camera. BUR is easily obtained and thought to be useful as a semi-quantitative index of brain perfusion.
PracticeClinical medicine
Keywords99mTc-HMPAO, Cerebral blood flow, RI angiography, SPECT, Brain uptake ratio.

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