Japanese |
Title | 99mTc-HMPAOを用いた脳血流量の半定量的指標の簡便な算出法 |
Subtitle | 原著 |
Authors | 宮崎吉春*, 絹谷清剛**, 利波紀久** |
Authors(kana) | |
Organization | *公立能登総合病院中央放射線部, **金沢大学医学部核医学教室 |
Journal | 核医学 |
Volume | 31 |
Number | 6 |
Page | 551-558 |
Year/Month | 1994/6 |
Article | 原著 |
Publisher | 日本核医学会 |
Abstract | 「要旨」99mTc-HMPAOシンチグラフィを用い, 脳血流量の目安となり非侵襲的に得られる新しい指標(brain uptake ratio, BUR)を考案し, 松田らが報告した指標(brain perfusion index, BPI)と比較した. 104例の左右大脳半球208部位において, 99mTc-HMPAO静注後の大動脈弓部の放射能通過量に対する脳内集積率をBURとして算出し, BPIと比較したところ, BURはBPIと有意の相関を示した(r=0.965, p<0.01). SPECT画像のデータを用いることにより, 深部あるいは後頭部の情報もBURによく反映された. BURは小視野ガンマカメラでも算出可能であり, 脳血流量を半定量化する指標として簡便かつ有用と考えられる. |
Practice | 臨床医学:一般 |
Keywords | 99mTc-HMPAO, Cerebral blood flow, RI angiography, SPECT, Brain uptake ratio. |
English |
Title | A Simple Method to Obtain Semi-quantitative Index of Brain Perfusion Using 99mTc-HMPAO |
Subtitle | Original Articles |
Authors | Yoshiharu MIYAZAKI*, Seigo KINUYA**, Norihisa TONAMI** |
Authors(kana) | |
Organization | *Section of Nuclear Medicine, Noto General Hospital, **Department of Nuclear Medicine, School of Medicine, Kanazawa University |
Journal | The Japanese Journal of nuclear medicine |
Volume | 31 |
Number | 6 |
Page | 551-558 |
Year/Month | 1994/6 |
Article | Original article |
Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
Abstract | [Summary] We developed a new noninvasive index (brain uptake ratio, BUR) inferring brain perfusion using 99mTc-HMPAO scintigraphy, and compared with the index (brain perfusion index, BPI) reported by Matsuda, et al. BUR was obtained for 208 cerebral hemispheres from 104 cases as a ratio of radioactivity in a brain against that passing through an aortic arch. BUR correlated well with BPI (r=0.965, p<0.01). Information in deep or occipital regions was reflected well to BUR when data of SPECT images were used. BUR can be obtained even with a small field-of-view gamma camera. BUR is easily obtained and thought to be useful as a semi-quantitative index of brain perfusion. |
Practice | Clinical medicine |
Keywords | 99mTc-HMPAO, Cerebral blood flow, RI angiography, SPECT, Brain uptake ratio. |