| Japanese |
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| Title | 123I-MIBGシンチグラフィを用いる神経芽細胞腫の診断 |
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| Subtitle | 短報 |
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| Authors | 小泉満*, 沢田裕久**, 後藤政文***, 飯島渉***, 亘理勉**, 黒沢秀光****, 車田宏之****, 杉田憲一****, 古川利温**** |
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| Authors(kana) | |
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| Organization | *癌研究会附属病院放射線科, **獨協医科大学放射線科, ***放射線部, ****第二小児科 |
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| Journal | 核医学 |
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| Volume | 31 |
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| Number | 5 |
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| Page | 507-511 |
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| Year/Month | 1994/5 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」神経芽細胞腫の疑われた9症例に123I-metaiodobenzyl-guanidine(123I-MIBG)シンチグラフィを施行した. 腫瘍を有する4症例で陽性像が得られ, 腫瘍を有さない5症例で陰性であった. さらに, 化学療法で縮小した腫瘍は残存しているが腫瘍マーカー(neuron specific enolase)の陰性化した症例でも陽性像が得られ, 化学療法の効果判定にも使用できる可能性が示された. 123I-MIBGシンチグラフィは, 神経芽細胞腫の診断および経過観察に有用と考えられた. 「I. はじめに」神経芽細胞腫は, 小児悪性新生物の中では白血病に次いで多く, 腹部固形腫瘍では最も多い. その正確な診断は近年この疾患にマススクリーニングが用いられるようになり重要性が増してきた. 131I-metaiodobenzyl-guanidine(MIBG)が褐色細胞腫, 神経芽細胞腫等の疾患に集積し, その有用性が報告されてきた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-MIBG, Neuroblastoma, Diagnosis. |
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| English |
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| Title | 123I-MIBG Scintigraphy in Patients with Neuroblastoma |
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| Subtitle | Short Communications |
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| Authors | Mitsuru KOIZUMI*, Hirohisa SAWADA**, Masabumi GOTO***, Ayumu IIJIMA***, Tsutomu WATARI**, Hidemitsu KUROSAWA****, Hiroyuki KURUMADA****, Ken-ichi SUGITA****, Toshiharu FURUKAWA**** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Center Institute Hospital, **Department of Radiology, ***Central Radiology Service, ****Second Department of Pediatrics, Dokkyo Medical University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 31 |
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| Number | 5 |
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| Page | 507-511 |
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| Year/Month | 1994/5 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] 123I-meta-iodobenzylguanidine (123I-MIBG) scintigraphy was performed in 9 patients who were suspected to have a neuroblastoma. Positive images were obtained in 4 patients who had a neuroblastoma. Negative images were obtained in 5 patients who did not have a neuroblastoma. 123I-MIBG scan revealed an active tumor in a patient who had received intensive chemotherapy for the recurrence of neuroblastoma with returning of all tumor markers including neuron specific enolase to normal range. This indicated that 123I-MIBG scan can be used to assess the effect of therapy. |
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| Practice | Clinical medicine |
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| Keywords | 123I-MIBG, Neuroblastoma, Diagnosis. |
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