| Japanese |
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| Title | 99mTc-MAG3を用いた動態因子分析による腎機能評価 |
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| Subtitle | 短報 |
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| Authors | 細川知紗*, 牛嶋陽*, 岡村光英**, 河辺譲治*, 波多信*, 小田淳郎*, 越智宏暢** |
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| Authors(kana) | |
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| Organization | *大阪市立大学医学部放射線医学教室, **核医学研究室 |
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| Journal | 核医学 |
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| Volume | 31 |
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| Number | 5 |
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| Page | 501-505 |
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| Year/Month | 1994/5 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」慢性腎障害症例に対し, 新しい腎シンチ製剤である99mTc-mercapto-acetyltriglycine(MAG3)を用い, その動態をfactor analysis(因子分析)により解析し腎機能評価への応用について検討した. MAG3370MBqを静注直後より30分間データ収集を行い, 一回循環像, 経時的腎シンチ像を得ると同時に因子分析を試みた. MAG3は一回循環で大半が腎から排泄されることより, 因子分析を行ったところ, 10例中8例(Cre≦2.9mg/dl)で, 腎実質成分と腎盂成分を反映する2因子に分離しえ, これらは, 各区域レノグラムに相当した. 残りの2例(Cre≧3.0mg/dl)では, 2因子分析では分離できず, 3因子分析が必要であった. 因子分析により, ROI設定を行わず客観性のある腎機能の評価が可能と考えられた. 「I. はじめに」臓器の機能評価においてそれが複数の機能から成る場合, 各機能を分離して把握することは重要で, その一つの方法として因子分析が応用されている. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-MAG3, Factor analysis, Chronic nephropathy. |
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| English |
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| Title | Evaluation of Renal Function by Factor Analysis Using 99mTc-MAG3 |
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| Subtitle | Short Communications |
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| Authors | Chisa HOSOKAWA*, Yo USHIJIMA*, Terue OKAMURA**, Joji KAWABE*, Makoto HATA*, Junro ODA*, Hironobu OCHI** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Osaka City University, **Division of Nuclear Medicine, Osaka City University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 31 |
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| Number | 5 |
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| Page | 501-505 |
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| Year/Month | 1994/5 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] The kinetics of 99mTc-mercapto-acetyltriglycine (MAG3), a new renal scintigraphic agent, was studied by factor analysis in patients with chronic renal disorders, and its application to assessment of the renal function was evaluated. Data were collected for 30 minutes from immediately after intravenous injection of MAG3 at 370 MBq, the first pass image and serial renal scintigrams were obtained, and factor analysis was attempted simultaneously. Since most of MAG3 is excreted via the kidney during the first pass, factor analysis was performed. Two factors reflecting renal parenchymal components and pelvic components could be separated in 8 (Cre<=2.9 mg/dl) of 10 patients, and they corresponded with respective segmental renograms. In the remaining 2 (Cre>=3.0 mg/dl), separation was impossible by 2-factor analysis, and 3-factor analysis was needed. Factor analysis is considered to allow objective evaluation of renal function without setting the ROI. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-MAG3, Factor analysis, Chronic nephropathy. |
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