Japanese
Title201Tl-99mTcサブトラクションシンチグラフィによる原発性および二次性副甲状腺機能亢進症の局在診断
Subtitle原著
Authors鐘ヶ江香久子*, 伊藤和夫*, 加藤千恵次*, 永尾一彦*, 中駄邦博*, 藤森研司*, 古舘正從*
Authors(kana)
Organization*北海道大学医学部核医学講座
Journal核医学
Volume31
Number5
Page441-449
Year/Month1994/5
Article原著
Publisher日本核医学会
Abstract「要旨」過去10年間に施行した副甲状腺シンチグラフィ91例中59例で手術がなされ, 腺腫あるいは過形成と確認された57例について本検査法の診断率の分析を行った. 疾患の内訳は一次性38例, 二次性18例, 両者の合併が1例, また組織型では, 腺腫28例, 過形成28例, 両者の合併1例であった. 腺腫(30腺)の重量は0.100〜11.700g(1.840±0.446g(mean±SE)), 過形成(88腺)では0.025〜7.000g(0.623±0.100g)に分布していた. 全体, 一次性, 二次性, 腺腫, および過形成のsensitivityはそれぞれ47%, 69%, 34%, 87%, 33%, specificityは54%, 55%, 57%, 57%, 52%, accuracyは49%, 62%, 40%, 72%, 38%であった. 1g以下の描出率は, 全腺で39%, 腺腫および過形成ではそれぞれ94%および27%と腺腫で非常に良好であった. 本検査法は過形成よりむしろ腺腫の検出に有用である.
Practice臨床医学:一般
KeywordsHyperparathyroidism, Parathyroid, Scintigraphy.
English
TitleDetection and Localization of Parathyroid Adenomas and Hyperplasias in Patients with Hyperparathyroidism Using Thallium-201/Technetium-99m Parathyroid Subtraction Scintigraphy
SubtitleOriginal Articles
AuthorsKakuko KANEGAE, Kazuo ITOH, Chietsugu KATO, Kazuhiko NAGAO, Kunihiro NAKADA, Kenji FUJIMORI, Masayori FURUDATE
Authors(kana)
OrganizationDepartment of Nuclear Medicine, Hokkaido University, School of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume31
Number5
Page441-449
Year/Month1994/5
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] 201Tl/99mTc subtraction scintigraphy (TTS) has been recognized as a useful procedure in the preoperative localization of hyperfunctioning parathyroid glands. Ninety-one patients suspected of hyperparathyroidism (HPT) were studied with TTS for the localization of lesions and 59 patients out of those had a neck exploration and parathyroidectomy which allowed for clinical correlation of pathologic findings with the imaging results. The weight of 30 glands of adenoma ranged 0.100 to 11.700g (1.840 +- 0.446g (mean+-SE)). The weight of 88 glands of hyperplasia ranged 0.025 to 7.000g (0.623+-0.100g). Overall sensitivity and specificity were 47% and 54%, respectively. The sensitivity for the adenoma and the hyperplasia was 87% and 33%, respectively. The specificity for them was 57% and 52%. There was significant difference for the detection between adenomas and hyperplasias. TTS is more useful for the localizing diagnosis of parathyroid adenomas than parathyroid hyperplasia in a patient with hyperfunctioning parathyroid state.
PracticeClinical medicine
KeywordsHyperparathyroidism, Parathyroid, Scintigraphy.

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