| Japanese |
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| Title | 99mTc-Tetrofosmin心筋シンチグラフィによる肥大型心筋症の心筋灌流および形態評価 |
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| Subtitle | 原著 |
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| Authors | 大槻克一*, 杉原洋樹**, 谷口洋子*, 馬本郁男*, 中川達哉*, 中村隆志*, 東秋弘*, 河野義雄*, 足立晴彦*, 落合正和***, 前田知穂**, 中川雅夫* |
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| Authors(kana) | |
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| Organization | *京都府立医科大学第二内科, **放射線科, ***京都府立洛東病院循環器科 |
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| Journal | 核医学 |
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| Volume | 31 |
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| Number | 4 |
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| Page | 309-318 |
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| Year/Month | 1994/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 新しい心筋灌流イメージング製剤である99mTc-Tetrofosminにより肥大型心筋症の心筋灌流と左室形態を同時に評価し, その有用性を検討した. 肥大型心筋症 (HCM) 10例を対象とした. 同日に施行した運動負荷時および安静時の99mTc-TetrofosminによるSPECT像を18分画し, 集積程度を5段階にスコア化して同時期の201Tl像と比較した. また, 安静時に99mTc-Tetrofosmin Gated SPECTを施行し, 心エコー図, 左室造影所見と対比した. 99mTc-Tetrofosminと201Tlの各領域のスコアの完全一致率は負荷時, 安静時ともに75.0%であり, 一段階以内の一致率はそれぞれ97.8%, 97.2%であった. 99mTc-Tetrofosminは201Tlに比し画像が鮮明であった. Gated SPECTより求めた中隔壁厚, 自由壁厚および中隔/自由壁厚比は, 心エコー図より求めた値と比較的良好な相関が認められ, 左室内腔形態は左室造影所見と近似した. 99mTc-Tetrofosmin心筋シンチグラフィは, HCMの心筋灌流異常の検出および形態評価に有用であると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Hypertrophic cardiomyopathy, 99mTc-Tetrofosmin, ECG gated SPECT. |
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| English |
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| Title | Evaluation of Myocardial Perfusion and Ventricular Shape in Hypertrophic Cardiomyopathy Using 99mTc-Tetrofosmin Scintigraphy : Comparison with 201Tl Myocardial Scintigraphy |
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| Subtitle | Original Articles |
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| Authors | Katsuichi OHTSUKI*, Hiroki SUGIHARA**, Yoko TANIGUCHI*, Ikuo UMAMOTO*, Tatsuya NAKAGAWA*, Takashi NAKAMURA*, Akihiro AZUMA*, Yoshio KOHNO*, Haruhiko ADACHI*, Masakazu OCHIAI***, Tomoho MAEDA**, Masao NAKAGAWA* |
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| Authors(kana) | |
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| Organization | *Second Department of Medicine, **Department of Radiology, Kyoto Prefectural University of Medicine, ***Department of Cardiology, Kyoto Prefectural Rakuto Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 31 |
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| Number | 4 |
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| Page | 309-318 |
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| Year/Month | 1994/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Hypertrophic cardiomyopathy (HCM) is known to have the impairment of myocardial perfusion as well as irregularly hypertrophic myocardium. To evaluate myocardial perfusion and ventricular shape in HCM, 99mTc-Tetrofosmin scintigraphy was performed after exercise (Ex) and at resting state (Re) in 10 patients with HCM and was compared with early image (Ea) and delayed image (De) of 201Tl scintigraphy performed after exercise. SPECT images of both 99mTc-Tetrofosmin and 201Tl scintigraphy were analyzed with five scaled visual scores set in 18 segments. The complete concordance ratio between 99mTc-Tetrofosmin (Ex and Re) and 201Tl (Ea and De) images in segmental analysis was 75%. Image quality of 99mTc-Tetrofosmin was seemed to be superior to that of 201Tl scintigraphy. In 9 patients with HCM, 99mTc-Tetrofosmin scintigraphy was performed under the ECG gating and the thickness of septal and free wall was measured. Good correlation was observed with the data by ultrasound cardiography (r=0.79, p<0.002 in wall thickness, r=0.84, p<0.01 in the ratio of septal wall thickness to free wall thickness) . Left ventricular shape (ventricular long axis) was closely resemble to that of left ventriculography by contrast medium. In conclusion, 99mTc-Tetrofosmin scintigraphy is useful for the evaluation of myocardial morphology as well as perfusion abnormality. |
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| Practice | Clinical medicine |
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| Keywords | Hypertrophic cardiomyopathy, 99mTc-Tetrofosmin, ECG gated SPECT. |
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