| Japanese |
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| Title | 81mKr持続注入法による冠動脈疾患の運動負荷時右室駆出率の検討 - 冠動脈病変部位および左室機能との関連について - |
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| Subtitle | 原著 |
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| Authors | 久保田修平* |
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| Organization | *群馬大学医学部第二内科 |
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| Journal | 核医学 |
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| Volume | 31 |
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| Number | 2 |
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| Page | 163-173 |
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| Year/Month | 1994/2 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 冠動脈疾患の運動負荷時右室機能を規定する因子を解析するため, 冠動脈疾患35例と正常対照12例に81mKr運動負荷右心プールシンチグラフィを施行した. 疾患群をI群:右冠動脈には病変のない例, II群:右冠動脈の主要右室枝分岐部より遠位に病変のある例, III群:主要右室枝分岐部より近位に病変のある例に分けた. 運動負荷時の右室駆出率の反応は対照群に比しII群, III群では不良で, 特にIII群では低下した. 右室反応不良はIII群11例全例, II群8例中5例に見られたがI群では16例中2例のみであった. I群, II群中で右室反応不良を示した7例中5例は多枝病変例であった. 右室駆出率と左室駆出率の変化率には有意な相関を認めなかった. 冠動脈疾患の運動負荷時右室機能障害の要因として最も重要なのは右冠動脈近位部病変であると結論する. ただし多枝病変例では右室後負荷増大により右室機能障害を生ずる可能性も推定される. |
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| Practice | 臨床医学：一般 |
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| Keywords | 81mKr, Right ventricular ejection fraction, Coronary artery disease, Proximal right coronary artery stenosis. |
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| English |
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| Title | Assessment of Right Ventricular Ejection Fraction during Exercise in Coronary Artery Disease by Multiple-Gated Equilibrium Scintigraphy Using Continuous Infusion of 81mKr : Relationship with the Location of Coronary Artery Stenosis and Left Ventricular Function |
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| Subtitle | Original Articles |
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| Authors | Shuhei KUBOTA |
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| Authors(kana) | |
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| Organization | Second Department of Internal Medicine, Gunma University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 31 |
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| Number | 2 |
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| Page | 163-173 |
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| Year/Month | 1994/2 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] To study the effect of location of coronary artery lesions on right ventricular (RV) function, exercise 81mKr multiple gated equilibrium scintigraphy was performed in 35 cases with coronary artery disease and 12 control subjects. Thirty five patients were divided into three groups:group I;those without right coronary artery (RCA) stenosis (n=16) , group II;those with stenosis of RCA distal to the origin of the major RV branch (n=8) and group III;those with proximal RCA stenosis (n=11) . RV ejection fraction (RVEF) at rest was not significantly different among four groups. However, increase of RVEF during supine bicycle exercise was markedly suppressed in group III compared with any other three groups. Abnormal RVEF response to exercise was seen in all 11 cases of group III and five of eight cases of group II, while only two of 16 cases of group I showed abnormal RVEF response. Five of seven cases who demonstrated abnormal RVEF response without proximal RCA stenosis had multiple coronary vessel disease. On the other hand, the left ventricular (LV) response was more suppressed in group II than in group III, and no significant correlation was observed between RVEF and LVEF responses during exercise. The impairment of RVEF response to exercise seemed to be related to the proximal RCA stenosis. However, in the presence of multiple coronary vessel disease, increased RV afterload during exercise may also play a role in abnormal RVEF response in coronary artery disease. |
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| Practice | Clinical medicine |
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| Keywords | 81mKr, Right ventricular ejection fraction, Coronary artery disease, Proximal right coronary artery stenosis. |
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