| Japanese |
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| Title | 移植腎における99mTc-MAG3による各種機能指標の算出 - 99mTc-DTPAおよび123I-OIHとの比較 - |
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| Subtitle | 原著 |
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| Authors | 小泉潔*, 山口元司*, 遠山敬司*, 内山暁*, 山田豊**, 上野精** |
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| Authors(kana) | |
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| Organization | *山梨医科大学医学部放射線医学教室, **泌尿器科学教室 |
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| Journal | 核医学 |
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| Volume | 31 |
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| Number | 1 |
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| Page | 17-25 |
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| Year/Month | 1994/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」新しく開発された99mTc標識の尿細管分泌物質である99mTcメルカプトアセチルトリグリシン (99mTc-MAG3) を用いて10例の移植腎を対象に腎動態シンチグラフィを行い, 各種機能指標を算出し, 99mTc-DTPAや123I-OIHと比較した. MAG3の腎摂取率はOIHやDTPAとよい相関を示したが, OIHよりは低く, DTPAよりは高い値であった. MAG3のレノグラム指標はDTPAやOIHとよい相関を示したが, 排泄はOIHより遅く, DTPAより速い値であった. 膀胱/腎集積比もDTPAやOIHとよい相関を示したが, OIHよりは低く, DTPAよりは高い値であった. 以上, MAG3の集積率や排泄率はOIHよりやや劣るが, DTPAよりは明らかに優れ, 99mTc標識である利点も考慮し, 移植腎における各種機能指標の算出が十分可能な薬剤と思われる. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-MAG3, Renal scintigraphy, Transplanted kidney |
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| English |
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| Title | Functional Parameters Calculated by 99mTc-MAG3 in Transplanted Kidney |
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| Subtitle | Original Articles |
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| Authors | Kiyoshi KOIZUMI*, Motoji YAMAGUCHI*, Keishi TOOYAMA*, Guio UCHIYAMA*, Yutaka YAMADA**, Akira UENO** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **Department of Urology, Yamanashi Medical University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 31 |
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| Number | 1 |
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| Page | 17-25 |
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| Year/Month | 1994/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] A newly developed 99mTc-labeled renal tubular agent, 99mTc-mercaptoacetyltriglycine (99mTc-MAG3) was evaluated and compared with 99mTc-DTPA and 123I-OIH in 10 patients with a transplanted kidney. Renal uptake of MAG3 correlated well with both DTPA and OIH;however, these uptake values of MAG3 were lower than those of OIH and higher than those of DTPA. Renogram parameters also correlated well with each other, but excretion of MAG3 was slower than that of OIH and faster than that of DTPA. The bladder to kidney ratio of MAG3 also correlated well, but these ratios of MAG3 were lower than those of OIH and higher than those of DTPA. In conclusion, MAG3 is a promising agent for evaluating the function of transplanted kidney. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-MAG3, Renal scintigraphy, Transplanted kidney |
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