Japanese
Title小児腎疾患経過観察における123I-Orthoiodohippurateシンチグラフィ
Subtitle原著
Authors岡田淳一*, 大西洋*, 眞山和徳**, 福本泰彦**
Authors(kana)
Organization*成田赤十字病院放射線科, **小児科
Journal核医学
Volume31
Number1
Page11-15
Year/Month1994/1
Article原著
Publisher日本核医学会
Abstract「要旨」5歳から15歳の慢性糸球体系腎疾患患者31例を対象に, 123I-Orthoiodohippurate (以下OIH) 腎シンチグラフィを行いその有用性を検討した. 病理診断の得られている慢性糸球体腎炎, 治療抵抗性のネフローゼ症候群では, レノグラム型が正常型ではなく, Tmax値やT1/2値が延長する例が多かった. 123I-OIHシンチグラフィは, 慢性糸球体疾患における軽度の腎機能低下を血中BUN濃度, クレアチニン濃度, クレアチニンクリアランス, PSP検査などの検査法よりも鋭敏にとらえられる可能性が示された. 持続する血尿, タンパク尿を示す症例群の中にも, レノグラムでTmax値やT1/2値の延長を示す症例が見られ, 腎機能の低下が疑われた. 低被曝下に容易に腎機能を評価できる123I-OIHシンチグラフィは小児腎疾患の経過観察に有用と考えられる.
Practice臨床医学：一般
Keywords123I-OIH, Renoscintigraphy, Chronic glomerulonephritis, Nephrotic syndrome.
English
Title123I-OIH Renoscintigraphy in Children with Chronic Disorder of Glomerulus
SubtitleOriginal Articles
AuthorsJunichi OKADA*, Hiroshi OONISHI*, Kazunori SANAYAMA**, Yasuhiko FUKUMOTO**
Authors(kana)
Organization*Department of Radiology, **Department of Pediatrics, Narita Red Cross Hospital
JournalThe Japanese Journal of nuclear medicine
Volume31
Number1
Page11-15
Year/Month1994/1
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] To evaluate the usefulness of 123I-orthoiodohippurate (OIH) renography, 31 patients with chronic disorder of glomerulus, from 5 years to 15 years old, were studied. In chronic glomerulonephritis and nephrotic syndrome with resistance to steroid therapy, Tmax and T1/2 of the timeactivity curve were statistically prolonged. Most of the renograms (time-activity curves) of the patients showed the hypofunction pattern. In most of the patients, other laboratory data, including BUN, PSP test and creatine clearance, didn't show abnormal values. 123I-OIH scan was considered to be a sensitive and useful method to evaluate the renal function in pediatric patients with chronic glomerulonephritis.
PracticeClinical medicine
Keywords123I-OIH, Renoscintigraphy, Chronic glomerulonephritis, Nephrotic syndrome.

【全文PDF】