Japanese
Title光刺激に対する脳血流変化の刺激時間依存性
Subtitle《技術報告》
Authors桑原康雄*, 一矢有一*, 大塚誠**, 佐々木雅之**, 赤司祐子*, 福村利光*, 吉田毅*, 増田康治*, 一宮厚***
Authors(kana)
Organization*九州大学医学部放射線科, **九州大学医学部生体防御医学研究所, ***九州大学医学部精神科
Journal核医学
Volume30
Number12
Page1491-1495
Year/Month1993/12
Article報告
Publisher日本核医学会
Abstract「要旨」 健常ボランティア5名を対象に光刺激に対する脳血流変化の刺激時間依存性を検討した. 脳血流はH215Oボーラス静注法を用い, 視覚遮断時, 光刺激開始2分後と7分後に測定した. 刺激開始2分後では左一次視覚領で19.6±7.9%(平均±SD, 範囲 : 8.9〜27.6%), 右側で23.2±13.6%(2.5〜35.8%)血流が増加した. 7分後では左側で平均25.3±20.0%(1.8〜49.7%), 右側で25.3±16.4%(3.5〜44.5%)血流が増加し, 2分後と7分後では両者に有意差はなく, 慣れの影響はほとんどないと考えられた. 「I. はじめに」 光刺激により後頭葉一次視覚領において脳糖代謝あるいは脳血流が増加することはよく知られているが, 脳血流変化の刺激時間依存性をH215Oボーラス静注法とポジトロンCTを用いて検討した. 「II. 対象ならびに方法」 対象は健常ボランティア5名(25〜40歳, 平均32.6歳, すべて右効き)である.
Practice臨床医学:一般
KeywordsCerebral blood flow, Positron emission tomography, Photic stimulation, Taming effect of photic stimulation
English
TitleStimulus Time Dependence of Cerebral Blood Flow Response to Photic Stimulation
SubtitleTechnical Reports
AuthorsYasuo KUWABARA*, Yuichi ICHIYA*, Makoto OTSUKA**, Masayuki SASAKI*, Yuko AKASHI*, Tsuyoshi YOSHIDA*, Toshimitsu FUKUMURA*, Kouji MASUDA*, Atsushi ICHIMIYA***
Authors(kana)
Organization*Department of Radiology, ***Department of Psychiatry, Faculty of Medicine, Kyushu University, **Department of Radiology, Medical Institute of Bioregulation, Kyushu University
JournalThe Japanese Journal of nuclear medicine
Volume30
Number12
Page1491-1495
Year/Month1993/12
ArticleReport
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] The time dependency of rCBF response to photic stimulation in the primary visual cortices was studied using H215O bolus-injection and PET. The subjects consisted of 5 normal volunteers aged from 25 to 40 years old. Their regional CBF was measured at 2 min and 7 min after the start of photic stimulation (frequency, 10 Hz). The percentage increases of rCBF were 19.6+-7.9% (mean+-SD, range : 8.9-27.6%) in the primary visual cortex on the left side and 23.2+-13.6% (2.5-35.8%) on the right side at 2 min, respectively, while, in comparison, they were 25.3+-20.0% (1.8-49.7%) on the left side and 25.3+-16.4% (3.5-44.5%) on the right side at 7 min, respectively. No significant difference was found in the rCBF responses between at 2 min and 7 min. Therefore, the taming effect does not need to be considered when carrying out a photic stimulation study.
PracticeClinical medicine
KeywordsCerebral blood flow, Positron emission tomography, Photic stimulation, Taming effect of photic stimulation

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