Japanese
Title高安動脈炎8症例の核医学検査の検討
Subtitle《症例報告》
Authors菅一能*, 西垣内一哉*, 久米典彦*, 内迫博路*, 中西敬*, 梅本誠一**, 藤井崇史**, 福田信二**, 松崎益徳**
Authors(kana)
Organization*山口大学医学部放射線科, **山口大学医学部第二内科
Journal核医学
Volume30
Number12
Page1465-1473
Year/Month1993/12
Article報告
Publisher日本核医学会
Abstract「要旨」 高安動脈炎8例に行われた各種核医学検査の有用性を検討した. 5例でRIアンギオグラフィが大動脈弓部から分岐する諸動脈の血流動態の評価に用いられ, 4例で病変部が指摘された. 肺血流シンチグラフィは5例に行われ, 1例を除き胸部X線写真で異常所見はなかったが, 単発性あるいは多発性の血流低下〜欠損を認めた. 腎シンチグラフィは, 4例中3例で血流低下と腎機能障害を認めた. このうち1例では, CT, MRIおよびDSAでは腎動脈の狭窄の有無の評価が困難であった. 3例の負荷心筋シンチグラフィでは, 狭心症症状を有した1例と無症状の1例で虚血所見が検出された. なお6例では複数の核医学検査が行われたが, 5例で1検査以上に異常所見を認めた. 本症は稀で病初期には非特異的な症状を呈することが多く, 診断が遅れる傾向があるが, さまざまな血管や臓器の循環動態や機能障害を非侵襲的に評価し得る核医学検査は, スクリーニング検査として適していると思われた.
Practice臨床医学:一般
Keywords99mTc-MAA, Radionuclide angiography, Thallium-201, Renal scintigraphy, Takayasu's arteritis.
English
TitleEvaluation of Radionuclide Studies in the 8 Patients with Takayasu's Arteritis
SubtitleCase Reports
AuthorsKazuyoshi SUGA*, Kazuya NISHIGAUCHI*, Norihiko KUME*, Hiromichi UCHISAKO*, Takashi NAKANISHI*, Seiichi UMEMOTO**, Takashi FUJII**, Shinji FUKUDA**, Masunori MATSUZAKI**
Authors(kana)
Organization*Department of Radiology, Yamaguchi University School of Medicine, **Second Department of Internal Medicine, Yamaguchi University School of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume30
Number12
Page1465-1473
Year/Month1993/12
ArticleReport
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] We evaluated various radionuclide studies performed in the 8 patients with Takayasu's arteritis over the past six years. Radionuclide angiography was performed in 5 patients to investigate the lesions of the branches of the aortic arch, and it demonstrated abnormalities of the affected arteries in 4 patients. Pulmonary perfusion scan demonstrated single or multiple reduced perfusion sites in all the 5 patients examined, while chest radiographies of these patients did not show any abnormalities in the reduced perfusion sites except one case. Renal scintigraphy revealed reduced renal blood flow in 3 patients. In one of those patients, MRI, CT and DSA studies could not detect any stenotic change in the renal artery. Exercise thallium scan revealed myocardial ischemic changes in 2 patients. One of them had angina pectoris, but another patient did not have any complaints. Of the 6 patients who were examined more than one kind of radionuclide studies, five patients showed abnormalities in more than one study. Ambiguous symptoms at the initial stage and rareness of Takayasu's arteritis may delay diagnosis. Radionuclide studies, which can be performed easily and noninvasively to investigate various organs and to depict multiple vascular involvement, seem to be a useful diagnostic tool of this disease.
PracticeClinical medicine
Keywords99mTc-MAA, Radionuclide angiography, Thallium-201, Renal scintigraphy, Takayasu's arteritis.

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