| Japanese |
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| Title | 18F-fluorodeoxyglucose PET腹部良性疾患集積例の検討 |
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| Subtitle | 《原著》 |
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| Authors | 岡住慎一*, 榎本和夫*, 福長徹*, 菊池俊之*, 浅野武秀*, 磯野可一*, 有水昇**, 今関恵子**, 伊藤裕***, 山本宏**** |
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| Authors(kana) | |
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| Organization | *千葉大学医学部第二外科, **千葉大学医学部放射線科, ***千葉大学医学部附属病院放射線部, ****千葉県がんセンター消化器科 |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 12 |
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| Page | 1439-1443 |
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| Year/Month | 1993/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 18F-fluorodeoxyglucose (FDG) PETによる腫瘍診断は, 悪性腫瘍において糖代謝が亢進状態にある性質を利用したものである. しかし, 良性疾患の中にも高度のFDG集積を示すものがあり, 本法による良性悪性鑑別診断上, 偽陽性所見を呈する. 今回われわれは, 消化器良性疾患39例にFDG PETを施行し, FDG静注後60分におけるstatic studyより, 集積度を病変と血漿の放射能濃度比(Ci/Cp)を用いて評価した. Ci/Cp≧2の高集積を呈した例は11例で, 内訳は, 肝膿瘍4例, 骨盤膿瘍1例, 大網膿瘍1例, 慢性膵炎2例, 肝炎症性偽腫瘍1例, 後腹膜平滑筋腫1例, 膵solid and cystic tumor 1例であり, これら11例のCi/Cpは3.64±0.77であった. FDG集積部の病理組織所見の特徴は, 炎症細胞の高密度の集積像あるいは充実性腫瘍組織像であった. FDG PETによる腫瘍診断時においては, 高度の炎症および一部の良性充実性腫瘍が偽陽性所見を示すことを考慮する必要がある. |
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| Practice | 臨床医学：一般 |
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| Keywords | 18F-fluorodeoxyglucose, PET, Ci/Cp ratio, Benign disease. |
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| English |
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| Title | Evaluation of the Cases of Benign Disease with High Accumulation on the Examination of 18F-Fluorodeoxyglucose PET |
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| Subtitle | Original Articles |
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| Authors | Shinichi OKAZUMI*, Kazuo ENOMOTO*, Toru FUKUNAGA*, Toshiyuki KIKUCHI*, Takehide ASANO*, Kaichi ISONO*, Noboru ARIMIZU**, Keiko IMAZEKI**, Yutaka ITO***, Hiroshi YAMAMOTO**** |
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| Authors(kana) | |
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| Organization | *Second Department of Surgery, **Department of Radiology, ***Division of Radiology, Chiba University School of Medicine, ****Chiba Cancer Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 12 |
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| Page | 1439-1443 |
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| Year/Month | 1993/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] In this study 39 cases of abdominal benign disease were examined by PET using 18F-fluorodeoxyglucose (FDG), and 11 cases of them (i.e. 4 cases of liver abscess, 1 of pelvic abscess, 1 of omental abscess, 2 of chronic pancreatitis, 1 of inflammatory pseudotumor of liver, 1 of retroperitoneal leiomyoma and 1 of solid and cystic tumor of pancreas) which showed as high accumulation of FDG as malignant lesion were investigated of their clinical and pathological feature. We used Ci/Cp ratio as index to express the accumulation of FDG in the lesion, which was calculated from radioactivities of the lesion (Ci) and the plasma (Cp) at 60 mins after injection of FDG. The Ci/Cp ratio of the 11 cases was 3.64+-0.77. The pathological feature of the 9 inflammatory cases was high accumulation of inflammatory cells and that of the 2 benign tumor cases was solid proliferation of tumor cells. The serum of the 9 inflammatory cases showed high CRP value. It was considered that the high accumulation of FDG in inflammatory lesions was due to piles of FDG uptake of the many inflammatory cells, while the 2 benign tumors of high accumulation were considered that the tumor cell had as high glucose metabolism as malignancies. |
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| Practice | Clinical medicine |
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| Keywords | 18F-fluorodeoxyglucose, PET, Ci/Cp ratio, Benign disease. |
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