| Japanese |
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| Title | 慢性腎不全患者のジピリダモール負荷201Tl心筋シンチグラフィにおけるwashout rateの検討 - 肥大型心筋症との比較 - |
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| Subtitle | 《短報》 |
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| Authors | 松村要*, 千田豊**, 伊藤綱朗***, 水谷安秀**, 吉田亘孝***, 安田龍市***, 高木勲***, 中川毅* |
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| Authors(kana) | |
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| Organization | *三重大学医学部放射線科, **社会保険羽津病院内科, ***社会保険羽津病院放射線科 |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 11 |
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| Page | 1405-1409 |
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| Year/Month | 1993/11 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 慢性腎不全患者(CRF)14名を対象としてジピリダモール負荷201Tl心筋シンチグラフィを行った. 臨床的に虚血性心疾患は除外したが, 心エコーにて左室壁の肥厚を認めた(13±2mm). 3時間後のSPECTより求めたwashout rate(WR)は54.2±6.8%であり, コントロールの46.2±9.1%(n=9)に比して有意の高値を示した(p<0.05). これらのCRFでは貧血が見られ(ヘマトクリット値(Ht) 24.5±3.2%), それに伴う冠動脈血流量の増加がWR増加の一因であると考えた. 比較のため, 肥大型心筋症(HCM)9名にても同様に201Tl心筋シンチグラフィを行いWRを求めたところ, 26.9±11.4%と有意の低値を示した(p<0.01). HCM群のHtは44.6±3.6%と, 高値を示し(p<0.001), 血液濃縮の傾向を示した, CRF, HCM, コントロールの3群のWRとHtの間には有意の逆相関(r=-0.796, p<0.001)を認めた. これらの疾患における201Tl心筋シンチグラフィの診断にはこの点も考慮する必要があると考える. |
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| Practice | 臨床医学：一般 |
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| Keywords | Thallium myocardial scintigraphy, Chronic renal failure, Washout rate, Hypertrophic cardiomyopathy. |
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| English |
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| Title | Study of Washout Rate in Patients with Chronic Renal Failure by Dipyridamole 201Tl Myocardial Scintigraphy - Comparison with Hypertrophic Cardiomyopathy - |
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| Subtitle | |
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| Authors | Kaname MATSUMURA*, Yutaka SENDA**, Tsunao ITO***, Yasuhide MIZUTANI**, Nobutaka YOSHIDA***, Ryuichi YASUDA***, ISAO TAKAGI***, Tsuyoshi NAKAGAWA* |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Mie University School of Medicine, **Department of Medicine, ***Department of Radiology, Social Insurance Hazu Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 11 |
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| Page | 1405-1409 |
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| Year/Month | 1993/11 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Fourteen patients with chronic renal failure (CRF) were studied by dipyridamole 201Tl myocardial scintigraphy. In this study, patients with coronary heart disease were excluded by clinical findings. 201Tl SPECT was performed at 8 min after injection of dipyridamole (0.56 mg/kg) and at a 3-hr delayed interval, and washout rates (WR) were calculated. Because UCG showed left ventricular hypertrophy (thickness ; 13+-2 mm) in CRF, the WR values were compared with those of hypertrophic cardiomyopathy (HCM) (n=9). In CRF, an average WR was 54.2+-6.8% and was significantly higher than that in normal (46.2+-9.1%, p<0.05, n=9), though WR in HCM was significantly low (26.9+-11.4%, p<0.01). Hematocrit value was 24.5+-3.2% in CRF and was significantly lower than that in normal (37.8+-3.6%, p<0.001). On the other hands, hemoconcentration was observed in HCM (hematocrit ; 44.6+-3.6%, p<0.001). WR in CRF, HCM and normal had significant correlation with hematocrit values (r=-0.796, p<0.001). These results suggest that anemia or hemoconcentration may affect coronary blood flow and WR, and this should be considered when diagnosing coronary heart disease in CRF or HCM. |
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| Practice | Clinical medicine |
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| Keywords | Thallium myocardial scintigraphy, Chronic renal failure, Washout rate, Hypertrophic cardiomyopathy. |
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