Japanese
Title肝持続動注時の体位によるカテーテル灌流域の変化について - 99mTc-MAAによる検討 -
Subtitle《原著》
Authors曽根康博*, 荒井保明*, 向所敏文*, 中塚豊真*, 佐々木文雄*, 木戸長一郎*
Authors(kana)
Organization*愛知県がんセンター放射線診断部
Journal核医学
Volume30
Number11
Page1353-1358
Year/Month1993/11
Article原著
Publisher日本核医学会
Abstract「要旨」 肝動脈へ経皮的にカテーテルが留置されており, 肝全域の良好な造影が確認された転移性肝腫瘍20症例を対象に, 緩徐な肝動注時のカテーテル灌流域が体位によりどのような影響を受けるかを99mTc-MAAを用いて検討した. 各症例ごとにRI注入時の体位を変えて(臥位と座位), 2回の検査を1週間の間隔で施行した. 得られた両画像(臥位像と座位像)を, 肝左葉と右葉への分布の差, 肝外集積の有無等に着目して比較し, A群(ほぼ同じ集積パターンを示すもの), B群(軽度の差異を認めるもの), C群(著明な差異を認めるもの)の3群に分類した. その結果, A群は6例(30%), B群は8例(40%), C群は6例(30%)であった. 急速動注(いわゆるワンショット動注)と異なり, ポンプによる緩徐な動注時には注入時の体位により薬剤分布が変化する場合があることが推測された.
Practice臨床医学:一般
KeywordsHepatic arterial infusion chemotherapy, Implantable injection port, 99mTc-MAA perfusion scintigraphy, Drug distribution.
English
TitleChanges of Arterial Blood Flow Patterns by Patients' Posture during Hepatic Arterial Infusion Chemotherapy Assessed by 99mTc-MAA Perfusion Scintigraphy
SubtitleOriginal Articles
AuthorsYasuhiro SONE, Yasuaki ARAI, Toshifumi MUKAIJO, Atsuhiro NAKATSUKA, Fumio SASAKI, Choichiro KIDO
Authors(kana)
OrganizationDepartment of Diagnostic Radiology, Aichi Cancer Center
JournalThe Japanese Journal of nuclear medicine
Volume30
Number11
Page1353-1358
Year/Month1993/11
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Hepatic arterial perfusion scintigraphy (HAPS) with 99mTc-macroaggregated albumin (MAA) was performed to reveal the effect of patients' posture for the arterial blood flow patterns in hepatic arterial infusion (HAI) chemotherapy. 20 patients of liver metastases with the percutaneously implanted catheter into the hepatic artery underwent HAPS following administration of 99mTc-MAA at the supine and the upright position under one week interval. 10 ml of the saline with radionuclide was injected at a rate of 1 ml per minute. Aquired two images at the different position of each patient were compared and grouped into three classes ; similar, slightly different and different. Of 20 patients, 6 (30%) were judged as similar, 8 (40%) as slightly different, and 6 (30%) as different. These results suggest that the drug distribution can change by patients' posture in case of the slow rate HAI performed with continuous infusion pump.
PracticeClinical medicine
KeywordsHepatic arterial infusion chemotherapy, Implantable injection port, 99mTc-MAA perfusion scintigraphy, Drug distribution.

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