Japanese
Title骨転移で検出された癌患者の原発巣の診断
Subtitle原著
Authors中野俊一*, 長谷川義尚*, 井深啓次郎*, 橋詰輝巳*, 野口敦司*, 今岡真義**, 小松原良雄***
Authors(kana)
Organization*大阪府立成人病センターアイソトープ診療科, **外科, ***整形外科
Journal核医学
Volume30
Number9
Page1049-1054
Year/Month1993/9
Article原著
Publisher日本核医学会
Abstract「要旨」昭和60年4月から平成3年3月までの6年間に骨シンチグラフィを施行した症例のうち骨痛を訴えて受診し, 骨シンチグラフィ, 骨X線検査, 骨生検などで転移性骨腫瘍と診断された27例 (男性23例, 女性4例, 年齢41-79歳, 平均64.2歳) の原発巣検索の結果を調べた. 20例では原発巣が明らかとなった. 肺癌9例, 前立腺癌, 肝細胞癌各3例, 腎癌2例, 甲状腺癌, 副腎癌, 胸膜中皮腫各1例であった. 胸部X線, 喀痰細胞診, 腹部超音波検査, 前立腺性酸性フォスファターゼ, 生検組織診などにより診断の手がかりが得られたが, 骨転移の原発が肝癌かどうかの診断には99mTc-PMTシンチグラフィが有用であった. 7例では原発巣が不明のままであった. このうち6例で転移巣の生検が行われ, 腺癌4例, 未分化癌2例であった. 死亡例17例の平均生存期間は9.5か月, 生存4例, 転帰不明6例であった.
Practice臨床医学：一般
KeywordsBone scintigraphy, Bone metastasis, Primary tumor site, 99mTc-PMT scintigraphy.
English
TitleSurvey for Primary Tumor Site in Patients with Initial Clinical Presentation of Bone Metastasis
SubtitleOriginal Articles
AuthorsShunich NAKANO*, Yoshihisa HASEGAWA*, Keijirou IBUKA*, Terumi HASHIZUME*, Atsushi NOGUCHI*, Shingi IMAOKA**, Yoshio KOMATSUBARA***
Authors(kana)
Organization*Department of Nuclear Medicine, **Department of Surgery, ***Department of Orthopedic Surgery, The Center for Adult Diseases
JournalThe Japanese Journal of nuclear medicine
Volume30
Number9
Page1049-1054
Year/Month1993/9
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Among the patients who were examined with bone scintigraphy between April 1985 and March 1991, there were 27 patients whose initial clinical manifestation was bone metastasis and who were surveyed for the primary tumor site. The primary tumor site could be identified in 20 patients (74%) , consisting of 9 patients with lung cancer, 3 with prostate cancer, 3 with hepatoma, 2 with renal cancer, and one each with thyroid cancer, adrenal cancer, and pleural malignant mesothelioma. In 17 of the 20 patients, the primary site had been detected within two months after presentation. Examinations which were helpful in identifying the primary site included chest radiography, sputum cytology, abdominal sonography, serum prostatic acid phosphatase level and pathologic examination of biopsy specimens. 99mTc-PMT scintigraphy was useful in the diagnosis of the hepatoma when accumulation was observed at the metastatic sites. In 2 patients, lung cancer had been recognized using follow-up chest radiography 3 and 6 months after presentation, respectively. One patient was diagnosed at autopsy as having adrenal cancer. In 7 patients the primary site remains unknown. Histology examination of the biopsy specimen performed in 6 of these patients revealed 4 to be adenocarcinoma and 2 undifferentiated carcinoma. The average survival period of the 17 patients who died was 9.5 months. Four patients are alive, and the outcome in the remaining 6 could not be determined.
PracticeClinical medicine
KeywordsBone scintigraphy, Bone metastasis, Primary tumor site, 99mTc-PMT scintigraphy.

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