| Japanese |
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| Title | 虚血性心疾患診断におけるATP負荷心プールシンチグラフィの有用性 |
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| Subtitle | 短報 |
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| Authors | 藤永剛*, 村田啓**, 小宮山伸之***, 丸野広大**, 原正忠*, 小野口昌久****, 斉藤京子****, 大竹英二**, 岡村哲夫* |
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| Authors(kana) | |
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| Organization | *東京慈恵会医科大学第四内科, **虎の門病院放射線科, ***循環器センター内科, ****放射線部 |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 7 |
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| Page | 785-788 |
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| Year/Month | 1993/7 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」ATP負荷心プールシンチグラフィの有用性を評価するために, 虚血性心疾患7例および正常対照3例に対し体内赤血球標識法によるfirst pass法を用いて, 安静時およびATP負荷時の心プールシンチグラフィを施行した. 右前斜位(RAO)30度にて安静時像を収集した後, 投与速度0.16mg/kg/minにてATPを持続静注し, 投与開始4分後にATP負荷時像を収集した. ATP負荷により虚血性心疾患患者7例中5例(5領域)に局所壁運動低下を認め, 6例に左室駆出率(LVEF)の低下を認めた. 正常対照者3例では局所壁運動およびLVEFともに低下を認めなかった. 虚血性心疾患診断における本法の有用性が示唆された. 「I. はじめに」Dipyridamoleを用いた薬物負荷は従来よりの201Tl心筋シンチグラフィのみならず, 負荷心プールシンチグラフィや負荷心エコー等にも応用され, 現在では虚血性心疾患の評価法として定着している. |
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| Practice | 臨床医学：一般 |
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| Keywords | ATP, Radionuclide ventriculography, Ischemic heart disease. |
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| English |
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| Title | ATP Radionuclide Ventriculography ; Its Usefulness for the Evaluation of Ischemic Heart Disease |
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| Authors | Tsuyoshi FUJINAGA*, Hajime MURATA**, Nobuyuki KOMIYAMA***, Hirotaka MARUNO**, Masatada HARA*, Masahisa ONOGUCHI**, Kyoko SAITO**, Eiji OHTAKE**, Tetsuo OKAMURA* |
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| Authors(kana) | |
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| Organization | *Fourth Department of Internal Medicine, Jikei University School of Medicine, **Division of Nuclear Medicine, ***Cardiovascular Center, Toranomon Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 7 |
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| Page | 785-788 |
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| Year/Month | 1993/7 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]To evaluate the usefulness for the detection of ischemic heart disease (IHD), ATP first pass radionuclide ventriculography (RVG) was performed in 10 patients. Coronary angiography was performed in all patients. Among these patients, 2 had single vessel disease, 2 had double vessel disease, 3 had triple vessel disease, and 3 had normal coronary arteries. RVG was performed at rest, then, ATP was infused at the rate of 0.16 mg/kg/min and ATP-RVG was done 4 minutes later. The left ventricular ejection fraction (LVEF) was calculated, and the regional wall motion (RWM) was graded as normal, hypokinesis, akinesis, and dyskinesis. In the patients with coronary artery disease, RWM decreased in 5 of 7 patients and LVEF decreased in 6 of 7 patients by ATP. However, RWM and LVEF did not decrease in the patients with normal coronary arteries. These results suggested that ATP-RVG might provide useful information for the evaluation of IHD. |
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| Practice | Clinical medicine |
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| Keywords | ATP, Radionuclide ventriculography, Ischemic heart disease. |
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