| Japanese |
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| Title | 新生児脳疾患の123I-IMP SPECTによる評価 |
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| Subtitle | 原著 |
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| Authors | 大島統男*,†, 鈴木千鶴子**, 佐々木順子**, 鬼頭修**, 安河内浩*** |
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| Authors(kana) | |
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| Organization | *名古屋第一赤十字病院放射線科, **小児科, ***帝京大学医学部放射線科, †現;帝京大学医学部放射線科 |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 7 |
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| Page | 727-733 |
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| Year/Month | 1993/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」脳疾患が疑われた11人の新生児につき123I-IMP SPECTを使い評価した. 正常の1例では小脳虫部, 脳幹, 中脳, 視床および感覚運動皮質に左右対称的に高い集積を示した. 前頭葉では軽度血流が減少していた. 虚血性脳症の6例中2例は皮質だけでなく, 脳幹部への集積も広汎に減少し, 再分布も認めなかった. 1例は傍矢状野にてearlyおよびdelayed像で集積減少を示した. なおこれら3例は予後不良であった. 虚血性脳症の他の3例はearly像で傍矢状野で集積減少を認めたが, delayed像で再分布を認め予後も良好であった. 結節性硬化症の1例はCT上の高吸収域に一致しててんかん発作時に高い集積を示したが, 1年後では逆に集積減少を示す, 興味ある所見を呈した. 以上のように新生児の123I-IMPは成人と異なる特徴が得られた. さらにearly像とdelayed像を施行することにより, 患児の予後をもある程度予測し得ると思われる. |
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| Practice | 臨床医学：一般 |
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| Keywords | Newborn, Hypoxic ischemic encephalopathy, Tuberous sclerosis, 123I-IMP SPECT, Prognostic value. |
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| English |
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| Title | Evaluation of Newborns with Brain Disease Using 123I-IMP SPECT |
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| Subtitle | |
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| Authors | Motoo OSHIMA*, Chizuko SUZUKI**, Junko SASAKI**, Osamu KITOH**, Hiroshi YASUKOCHI* |
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| Organization | *Department of Radiology, Teikyo University School of Medicine, **Department of Pediatrics, Nagoya First Red Cross Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 7 |
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| Page | 727-733 |
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| Year/Month | 1993/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]Eleven newborns with suspected cerebral disease were evaluated using 123I-IMP SPECT. In a normal subject, high uptake was shown in the sensorimotor cortex, thalamus, midbrain-brainstem, and cerebellar vermis. Decreased perfusion was also noted in the frontal lobe. In hypoxic ischemic encephalopathy (HIE), diffuse decreased uptake which showed no redistribution in the white matter was seen in two patients. These two patients had a poor prognosis. In one of the other 4 patients with HIE, persistent defect in parasagittal area was recognized and the patient also had a poor prognosis. In one of two patients with tuberous sclerosis, 123I-IMP SPECT showed high uptake in the area of increased density shown in CT. Thus, 123I-IMP SPECT of newborn has characteristic findings different from the adult. This tracer also might have a prognostic value of clinical improvement following HIE. |
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| Practice | Clinical medicine |
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| Keywords | Newborn, Hypoxic ischemic encephalopathy, Tuberous sclerosis, 123I-IMP SPECT, Prognostic value. |
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