| Japanese |
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| Title | RI動態画像を用いた移植腎機能評価の新しい試み - Rutland処理への因子分析法の導入 - |
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| Subtitle | 原著 |
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| Authors | 角田隆俊*, 平賀聖悟*, 飛田美穂*, 佐藤威*, 鈴木豊** |
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| Authors(kana) | |
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| Organization | *東海大学医学部移植学教室I, **放射線学教室I |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 7 |
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| Page | 717-726 |
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| Year/Month | 1993/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」99mTc-DTPAを用いた動態画像によって求められる入出力関数をRutlandの方法を用いて処理することにより, 臓器からの排泄が始まるまでの係数が得られ, これをわれわれは集積計数(Uptake coefficient:U. C. )と名づけた. この値は腎臓を対象とした場合, GFRと相関がある. 今回移植腎における腎実質性機能障害の急性期, 治療期, 回復期に対応するパラメータとして, これを用いることが可能か否かにつき検討を行った. パラメータ抽出の再現性を高めるために, 移植腎の各画素における時間放射能曲線に因子分析を適用した後, 得られた成分曲線を入出力関数に反映し, Rutlandの方法を用いて処理を行った. 因子分析法によるU. C. は, CCrとはr=0.75(P<0.01), Tauxeらの方法により求められたERPFとはr=0.67(P<0.01)の正相関を, sCrとはr=0.646(P<0.01)の逆相関を認めた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Grafted kidney, Glomerular filtration rate, Factor analysis, Rutland method. |
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| English |
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| Title | Evaluation of Renal Graft Function with Radionuclide Dynamic Images - Application of Modified Rutland's Analytical Method - |
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| Subtitle | Original Articles |
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| Authors | Takatoshi KAKUTA*, Seigo HIRAGA*, Miho HIDA*, Takeshi SATOH*, Yutaka SUZUKI** |
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| Authors(kana) | |
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| Organization | *Department of Transplantation I, **Department of Radiology, Tokai University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 7 |
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| Page | 717-726 |
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| Year/Month | 1993/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]An uptake coefficient (UC) is estimated with applying the method proposed by Rutland to the renal dynamic images with 99mTc-diethyltriamine pentaacetate (DTPA). UC estimated with this method is proportional to glomerular filtration rate in the original Rutland's method the cardiac and renal time-activity curves (TAC) were used for input and output functions, respectively. In this paper, our method of estimating an input and output function by applying factor analysis method to renal dynamic images and it's clinical application are presented. In 11 patients, UCs estimated by this modified method revealed good correlations between the UCs and CCr (r=0.75), between UCs and effective renal plasma flow (r=0.67), and inverse correlations between UCs and serum creatinine values (r=0.65). The results showed that UC in this method can be a useful parameter for grafted renal function. This method is simple in technique and applicable for the evaluation of split renal function in renal transplant donors. |
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| Practice | Clinical medicine |
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| Keywords | Grafted kidney, Glomerular filtration rate, Factor analysis, Rutland method. |
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