Japanese |
Title | 99mTc-HMPAO SPECTにて興味ある所見を示した脳死の1例 |
Subtitle | 症例報告 |
Authors | 土田龍郎*, 定藤規弘*, 西澤貞彦*, 的場直樹*, 藤田透*, 玉木長良*, 小西淳二*, 玉井直**, 新宮興***, 米倉義晴**** |
Authors(kana) | |
Organization | *京都大学医学部附属病院放射線核医学科, **京都大学医学部附属病院集中治療部, ***京都大学医学部附属病院救急部, ****京都大学医学部脳病態生理学講座 |
Journal | 核医学 |
Volume | 30 |
Number | 6 |
Page | 663-667 |
Year/Month | 1993/6 |
Article | 報告 |
Publisher | 日本核医学会 |
Abstract | 「要旨」 厚生省脳死判定基準により脳死と判定された78歳の男性に対し, 99mTc-d, l-hexamethyl-propyleneamine oxime (HMPAO)による脳血流single photon emission computed tomography (SPECT)を施行した. 厚生省脳死判定基準に基づく第1回目の脳死判定検査において脳死と判定された直後の脳血流SPECTでは, 脳内にトレーサの集積が見られ脳血流の存在が認められた. さらに3日後, 第3回目の脳死判定が行われた直後の脳血流SPECTにおいては脳内にトレーサの集積は全く認められなかった. 脳血流停止と機能喪失との間に時間的なずれが存在する場合, 患者の生存の可否が大きな問題となるが, 文献的には脳死判定されたにも関わらず脳血流を認めた症例が生存し得たとする報告もあり, 脳血流シンチグラフィは脳死確認の検査として重要であると考えられた. |
Practice | 臨床医学:一般 |
Keywords | 99mTc-HMPAO, Brain death, SPECT |
English |
Title | 99mTc-HMPAO SPECT in the Brain Death - A Case Report - |
Subtitle | |
Authors | Tatsuro TSUCHIDA*, Norihiro SADATO*, Sadahiko NISHIZAWA*, Naoki MATOBA*, Toru FUJITA*, Nagara TAMAKI*, Junji KONISHI*, Sunao TAMAI**, Ko SHINGU***, Yoshiharu YONEKURA**** |
Authors(kana) | |
Organization | *Department of Radiology and Nuclear Medicine, **Intensive Care Unit, ***Division of Emergency Medicine, ****Department of Brain Pathophysiology, Kyoto University Faculty of Medicine |
Journal | The Japanese Journal of nuclear medicine |
Volume | 30 |
Number | 6 |
Page | 663-667 |
Year/Month | 1993/6 |
Article | Report |
Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
Abstract | [Summary] Brain single photon emission computed tomography (SPECT) with 99mTc-d,l-hexamethyl-propyleneamine oxime (HMPAO) was performed twice in a 78-year-old man clinically diagnosed as brain death according to the standard criteria of the Japanese Ministry of Welfare. The first brain SPECT demonstrated the tracer accumulation in the brain, indicating preserved cerebral blood flow. The second brain SPECT performed 3 days later revealed cessation of the blood flow. In patients with preserved cerebral blood flow, the diagnosis of brain death cannot be made, even if they meet the existing criteria, because previous report noted the recovery in some of those patients. Brain perfusion SPECT plays an important role as a confirmatory test for the diagnosis of the brain death. |
Practice | Clinical medicine |
Keywords | 99mTc-HMPAO, Brain death, SPECT |