Japanese
Title放射線治療による唾液腺の67Ga-citrate集積亢進所見の検討
Subtitle原著
Authors吉田貴子*,†, 安久津徹*, 駒谷昭夫*, 山口昂一*
Authors(kana)
Organization*山形大学医学部放射線科, †現;信州大学医学部放射線科
Journal核医学
Volume30
Number6
Page637-641
Year/Month1993/6
Article原著
Publisher日本核医学会
Abstract「要旨」 放射線治療後のガリウムシンチグラフィにおける唾液腺の67Ga-citrate集積程度の治療後からの経時的な変化, および照射線量との関連について検討した. 対象は唾液腺を含む頭頸部領域に放射線治療が行われた症例のうち, ガリウムシンチグラフィが治療前後で合計4回以上行われた16例である. 集積程度は左右の耳下腺と顎下腺について視覚的に3段階に分類した. その結果, 全体の約半数は照射期間中から高集積を呈した. また高集積を呈する割合は30Gyを超えた群の方が30Gy以下のものと比べて多く, かつ高集積が遷延する傾向がみられた. 頭頸部領域の疾患のうち放射線治療が施行されたもので照射野内に唾液腺が含まれ, 特にその吸収線量の合計が30Gyを超えるような場合, ガリウムシンチグラフィのみで再発と頸部リンパ節転移の有無を検討する際は, 放射線治療終了後長期間経過した後も唾液腺への集積を考慮した慎重な判断が必要であると考えられた.
Practice臨床医学:一般
Keywords67Ga scintigraphy, 67Ga-citrate, Salivary glands, Radiotherapy
English
TitleRelation between Uptake of 67Ga-Citrate in Salivary Glands and Irradiation Doses
Subtitle
AuthorsTakako YOSHIDA, Tooru AKUTSU, Akio KOMATANI, Koichi YAMAGUCHI
Authors(kana)
OrganizationDepartment of Radiology, Yamagata University School of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume30
Number6
Page637-641
Year/Month1993/6
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] A retrospective study is performed 67Ga-citrate uptake by scintigraphy to evaluate the relation between gallium uptake of salivary glands and radiotherapy with special reference to radiation dose and period after initial irradiation. Sixteen patients with radiotherapy to their head and neck regions were studied, undergone 67Ga scintigraphy for four times or more were investigated. The following results were obtained: 1. About half of the total number of salivary glands increased the uptake of 67Ga-citrate during radiotherapy. 2. The number of salivary glands which increased uptake in a group which received more than 30 Gy was greater than that in a group less than 30 Gy, and many of them remained with increased activity for one year after radiotherapy. 3. Uptake in glands that received dose less than 30 Gy showed rapid increasement initially, and showed decrease of uptake in six months after the irradiation. We concluded that there was different tendency of gallium uptake between a group of patient with irradiation of less than 30 Gy and that with irradiation of more than 30 Gy. It is suggested that we must always consider gallium uptake of salivary glands for long term after the radiotherapy, when we discuss the recurrence or metastases of neck lymph nodes of patients, who have performed radiotherapy to their head and neck regions, especially high dose irradiation.
PracticeClinical medicine
Keywords67Ga scintigraphy, 67Ga-citrate, Salivary glands, Radiotherapy

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