| Japanese |
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| Title | ジピリダモール負荷心筋シンチグラフィにおける一過性虚血性左室拡大について |
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| Subtitle | 原著 |
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| Authors | 外山貴士*, Biray E.CANER*, 玉木長良**, 山本和高*, 中島鉄夫*, 小鳥輝男*, 高橋範雄*, 三船順一郎***, 大中正光***, 田中孝***, 石井靖* |
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| Authors(kana) | |
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| Organization | *福井医科大学放射線科, **京都大学医学部放射線核医学科, ***福井心臓血圧センター |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 6 |
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| Page | 605-611 |
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| Year/Month | 1993/6 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 ジピリダモール負荷心筋シンチグラフィで一過性虚血性左室拡大(TID; transient ischemic dilatation of the left ventricle)がみられる頻度および冠動脈病変との関連について検討した. 110例中16例(15%)にTIDが認められた. 冠動脈病変との関連では, 正常13例では全く認められず, 1枝病変では48例中3例(6%), 2枝病変では30例中5例(17%), 3枝病変では19例中8例(42%)でTIDが認められ, 2枝および3枝病変で有意に頻度が高かった(1VD vs. 3VD; p<0.005, 1VD vs. 2+3VD; P<0.025). またその程度も病変枝数が増えるにつれて強くなる傾向があった. TIDの有無で多枝病変を判定した場合, 感度は27%と低かったが特異度は95%と高く, 多枝病変診断の指標となり得ると思われた. またバイパス術前後で比較しえた5例全例で術後TIDは改善しており, バイパス術の効果判定の参考所見にもなると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Dipyridamole, Transient ischemic dilatation, Thallium-201, SPECT, Multivessel disease |
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| English |
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| Title | Transient Ischemic Dilatation of the Left Ventricle Observed on Dipyridamole-Stressed Thallium-201 Scintigraphy |
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| Authors | Takashi TOYAMA*, Biray E.CANER*, Nagara TAMAKI**, Kazutaka YAMAMOTO*, Tetsuo NAKASHIMA*, Teruo ODORI*, Norio TAKAHASHI*, Junichiro MIFUNE***, Masateru OHNAKA***, Takashi TANAKA***, Yasushi ISHII* |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Fukui Medical School, **Department of Radiology and Nuclear Medicine, Kyoto University School of Medicine, ***Fukui Cardiovascular Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 6 |
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| Page | 605-611 |
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| Year/Month | 1993/6 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] To assess clinical significance of transient ischemic dilatation of the left ventricle (TID) on dipyridamole-stressed 201Tl myocardial scintigraphy, 110 patients suspected with coronary artery disease, including 13 with normal coronary, 48 with single vessel disease, 30 with 2 vessel disease, and 19 with 3 vessel disease were analyzed. TID was visually and quantitatively assessed calculating the ratio of the area within the left ventricular region on the initial and delayed image (TID ratio). TID was observed in 3 of 1 vessel disease (6%), 5 of 2 vessel disease (17%), and 8 of 3 vessel disease (42%). None of normal coronary artery showed TID. In patients with multivessel disease (MVD), TID was observed more frequently (27%) than in patients with 1 vessel disease (6%) (p<0.025). Furthermore, the TID ratio tended to be higher (1.15+-0.11) than those with single vessel disease (1.03+-0.03). To identify patients with MVD, TID had a sensitivity of 27% and a specificity of 95%. ECG changes were observed more often in patients with TID than those without TID. Five patients showing TID underwent coronary artery bypass graft surgery, TID disappeared postoperatively in each patient. In conclusion, TID on dipyridamole 201Tl scan seems to be a specific although not sensitive marker for detecting MVD. |
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| Practice | Clinical medicine |
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| Keywords | Dipyridamole, Transient ischemic dilatation, Thallium-201, SPECT, Multivessel disease |
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