| Japanese |
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| Title | SPECTにて側頭頭頂葉の血流低下を認めたBinswanger型痴呆の1例 |
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| Subtitle | 症例報告 |
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| Authors | 羽生春夫*,**, 杉山壮*, 阿部晋衛*, 小林康孝*, 勝沼英宇*, 浅野哲一**, 新井久之**, 高崎優** |
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| Organization | *立川綜合病院表町病院, **東京医科大学老年科 |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 4 |
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| Page | 429-435 |
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| Year/Month | 1993/4 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」臨床的にBinswanger型痴呆と診断された1例に123I-IMP SPECTを施行し, 両側側頭頭頂葉領域の血流低下を認めた. この所見は従来Binswanger型痴呆で観察されている血流分布パターンとは異なり, アルツハイマー型痴呆のそれに類似していた. 本症例では側脳室後角の拡大傾向がみられ, 側頭頭頂葉深部白質病変が比較的高度であったことが, この血流分布異常の原因と考えられた. 今日, SPECTなどによる側頭頭頂葉の局所的異常の検出がアルツハイマー型痴呆の診断マーカーとして期待されているが, 稀にその他の疾患でも同様の血流分布を示す場合があり, これらの十分な認識と把握が鑑別診断の上で重要と考えられた. 「I. はじめに」Positron emission tomography(PET)やsingle photon emission CT(SPECT)などの三次元的局所脳循環代謝測定法の開発により, さまざまな痴呆性疾患にも臨床応用が加えられ, これらの病態把握における有用性が報告されている. |
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| Practice | 臨床医学：一般 |
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| Keywords | Binswanger-type dementia, Cerebral blood flow, SPECT, Temporoparietal hypoperfusion. |
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| English |
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| Title | A Case of Binswanger-Type Dementia with Bilateral Temporoparietal Hypoperfusion in SPECT |
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| Authors | Haruo HANYU*,**, Tsuyoshi SUGIYAMA*, Shinei ABE*, Yasutaka KOBAYASHI*, Hideyo KATSUNUMA*, Tetsuichi ASANO**, Hisayuki ARAI**, Masaru TAKASAKI** |
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| Authors(kana) | |
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| Organization | *Department of Internal Medicine, Tachikawa General Hospital, Omotemachi Hospital, **Department of Geriatric Medicine, Tokyo Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 4 |
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| Page | 429-435 |
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| Year/Month | 1993/4 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]We report a case of Binswanger-type dementia demonstrated bilateral temporoparietal hypoperfusion in SPECT with 123I-IMP. The perfusion pattern in the present case was different from those previously obtained in SPECT or PET studies of patients with Binswanger-type dementia, and was similar to regional abnormalities in patients with Alzheimer-type dementia. Temporoparietal hypoperfusion in this case is likely to be mediated by neuronal mechanisms via projection fibers as a result of the deep white matter lesions in the temporoparietal area. A decreased perfusion or metabolism in the temporoparietal area is considered to be a characteristic in patients with Alzheimer-type dementia, however, we should keep in mind that other cerebral disorders may also show a similar perfusion pattern. |
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| Practice | Clinical medicine |
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| Keywords | Binswanger-type dementia, Cerebral blood flow, SPECT, Temporoparietal hypoperfusion. |
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