| Japanese |
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| Title | 201Tl心筋SPECTを用いた右室負荷の定量的評価 |
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| Subtitle | 原著 |
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| Authors | 谷口洋子*, 宮尾賢爾**, 島正巳**, 北村誠**, 辻光**, 首藤達哉**, 杉原洋樹*, 中川雅夫* |
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| Organization | *京都府立医科大学第二内科, **京都第二赤十字病院内科 |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 4 |
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| Page | 371-376 |
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| Year/Month | 1993/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」右室負荷をきたした症例に201Tl心筋SPECTを施行し, MRIおよび心臓カテーテル検査の所見との対比より, 非侵襲的右室負荷評価法としての有用性を検討した. 右室負荷症例40例(平均年齢61.0±11.8歳)に施行した安静時201Tl心筋SPECT像の心室中部短軸像にて右室自由壁および左室自由壁に関心領域(2×2pixel)を設定し, 各カウントより, Tlカウント比(右室/左室)を求めた. このTlカウント比をMRIにて計測した壁厚比(右室壁厚/左室壁厚)および心臓カテーテル検査より算出した最大収縮期圧比(右室圧/左室圧)と対比検討した. Tlカウント比と壁厚比はY=0.73X+0.19(r=0.71, P<0.001)の相関関係を示した. Tlカウント比と圧比は圧負荷群でY=11.4X-0.049(r=0.85, P<0.001), 容量負荷群でY=0.51X+0.023(r=0.88, P<0.001)の異なる相関関係を示した. 201Tl心筋SPECTの定量的評価により右室負荷症例の右室, 左室の壁厚比および圧比が推定可能である. |
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| Practice | 臨床医学：一般 |
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| Keywords | 201Tl myocardial SPECT, Right ventricular overloading, Right ventricular systolic pressure, Right ventricular wall thickness. |
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| English |
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| Title | Quantitative Analysis of Right Ventricular Overloading by 201Tl Myocardial SPECT |
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| Subtitle | Original Articles |
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| Authors | Yoko TANIGUCHI*, Kenji MIYAO**, Masami SHIMA**, Makoto KITAMURA**, Hikari TSUJI**, Tatsuya SHUDO**, Hiroki SUGIHARA*, Masao NAKAGAWA* |
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| Authors(kana) | |
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| Organization | *Second Department of Medicine, Kyoto Prefectural University of Medicine, **Department of Medicine, Kyoto Second Red Cross Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 4 |
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| Page | 371-376 |
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| Year/Month | 1993/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]Clinical usefulness of quantitative analysis of right ventricular overloading was evaluated by 201Tl myocardial SPECT in comparison with cardiac catheterization and MRI. Seventy-four MBq of 201TlCl was intravenous injected and 201Tl myocardial SPECT was performed on 40 patients (mean age: 61.0 +- 11.8) with right ventricular overloading. Regions of interest (ROI) were selected on right and left ventricular walls in a midventricular short axis image of SPECT and uptake of each ROI were counted. The right ventricle (RV)/left ventricle (LV) 201Tl uptake ratio (R/L-Tl) was calculated. Wall thickness of RV and LV were measured on MRI and the RV/LV wall thickness ratio (R/L-WT) was calculated. RV and LV pressure were recorded in cardiac catheterization, and the RV/LV systolic pressure ratio (R/L-P) was calculated. There was significant positive correlation (Y=0.73X+0.19, r=0.71, p<0.001) between R/L-Tl and R/L-WT. R/L-Tl was positively correlated with R/L-P in patients with pressure overload (Y=1.14X-0.049, r=0.85, p<0.001) and in patients with volume overload (Y=0.51X+0.023, r=0.88, p<0.001) and the slope of the regression line in patients with pressure overload was significantly steeper than that in patients with volume overload (p<0.001). In conclusion, quantitative analysis of right ventricular overload by 201Tl myocardial SPECT is useful to estimate RV/LV wall thickness ratio and pressure ratio. |
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| Practice | Clinical medicine |
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| Keywords | 201Tl myocardial SPECT, Right ventricular overloading, Right ventricular systolic pressure, Right ventricular wall thickness. |
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