| Japanese |
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| Title | 99mTc-Tetrofosminの洗い出しの検討 |
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| Subtitle | 短報 |
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| Authors | 井上優介*, 町田喜久雄*, 本田憲業*, 間宮敏雄*, 高橋卓*, 釜野剛*, 鹿島田明夫* |
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| Organization | *埼玉医科大学総合医療センター放射線科学教室 |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 3 |
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| Page | 313-316 |
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| Year/Month | 1993/3 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 99mTc-Tetrofosminの洗い出しを, 9例の虚血性心疾患を疑われた患者において検討した. 運動負荷時および安静時に99mTc-Tetrofosminを静注し, その25分後および120分後からSPECTを施行した. また, 静注10分後, 150分後に前面像を撮像した. 前面像での検討では, 肝臓からの速やかな洗い出しが示された. 安静時にSPECTで求めたwashout rateは下壁において前壁や側壁より有意に高値であり(p<0.05), 負荷時にも統計的に有意ではなかったが同様の傾向が見られた. Washout rateは, いずれの領域でも負荷時の方が高く(前壁 ,側壁:p<0.01, 中隔:p<0.05, 下壁:N.S.), 安静時には前壁で3.4±14.0%, 側壁で2.7±22.5%, 負荷時には前壁で18.0±10.6%, 側壁で15.8±7.9%であった. 99mTc-Tetrofosmin SPECTの撮像時期の決定において, 肝臓から洗い出しが早期に起きること, および心筋からの洗い出しは負荷時により強いことを考慮する必要があると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-Tetrofosmin, Clearance, Myocardial imaging, Stress, Rest |
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| English |
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| Title | Clearance of 99mTc-Tetrofosmin from the Myocardium and the Adjacent Organs |
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| Subtitle | Short Communication |
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| Authors | Yusuke INOUE*, Kikuo MACHIDA*, Norinari HONDA*, Toshio MAMIYA*, Taku TAKAHASHI*, Tsuyoshi KAMANO*, Akio KASHIMADA* |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Saitama Medical Center, Saitama Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 3 |
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| Page | 313-316 |
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| Year/Month | 1993/3 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | We studied clearance of a new myocardial perfusion imaging agent, 99mTc-Tetrofosmin, from the myocardium and the adjacent organs in nine patients. 99mTc-Tetrofosmin was injected intravenously at stress and at rest, and SPECT images were obtained 25 min and 120 min later. Anterior view images were also obtained 10 min and 150 min after the injection to compare the myocardial clearance with those from the liver and lung. Clearance from the liver was faster than those from the myocardium and lung. Washout rate calculated with SPECT was higher for the inferior wall than for the anterior wall and lateral wall (p<0.05 at rest, N.S. at stress). The value was higher at stress in any region than at rest (the anterior wall and lateral wall, p<0.01; the septum, p<0.05; the inferior wall, N.S.). Washout rate for the anterior wall was 3.4+-14.0% at rest and 18.0+-10.6% at stress. The rate for the lateral wall was 2.7+-22.5% at rest and 15.8+-7.9% at stress. It was suggested that rapid hepatic clearance and high myocardial washout at stress may be important in determining the period between the injection of 99mTc-Tetrofosmin and the data acquisition for SPECT imaging. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-Tetrofosmin, Clearance, Myocardial imaging, Stress, Rest |
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