Japanese
TitleIn vivo核医学に関する放射性核種投与量の実態調査 - 医療放射線被曝の合理的低減に関する研究 -
Subtitle原著
Authors中村元俊*, 古賀佑彦*, 近藤武**, 立木秀一**, 安野泰史**, 江尻和隆**, 外山宏*, 竹下元*, 中根香織*, 徳田衛***, 横山貴美江****, 竹内昭**
Authors(kana)
Organization*藤田保健衛生大学医学部放射線科, **藤田保健衛生大学衛生学部診療放射線技術学科, ***藤田保健衛生大学医学部内科, ****藤田保健衛生大学病院放射線部
Journal核医学
Volume30
Number3
Page295-301
Year/Month1993/3
Article原著
Publisher日本核医学会
Abstract「要旨」 現在の医療用放射性核種の使用状況を把握するため104施設を対象にアンケート調査を行った. 回答のあった85施設の総検査数は年間119,614件で, 検査施行頻度は, (1)骨26.4%, (2)201Tl心筋15.5%, (3)67Ga 13.3%, (4)脳血流(123I-IMP)7%, (5)肝(99mTc-phytate)3.9%の順であった. 80%以上の施設で小児に対しては体重補正を行っていた. 過量投与施設は, 骨76.0%, 67Ga 93.0%, 201Tl 89.2%, IMP 8.5%であり, バイアル単位で高価なIMPは87年勧告が遵守される傾向を認めた. 実効線量当量の平均値は, (1)骨, (2)67Ga, (3)201Tlの順に大きかった. 201Tl, 67Ga, IMPは実投与量/申告投与量比が納入日/検定日放射能比と近似し, 納入日にバイアル内容すべてが投与されたと考えられた. 投与量に影響を及ぼす因子は, 1)through put, 2)核種の価格, 3)バイアル単位の販売などであり, 被曝の低減には医療側, 核種製造・販売業者, 測定装置製造業者の協力が必要であると考えられた.
Practice臨床医学：一般
KeywordsRadionuclide, Administrations and Dosage, Radiation protection, Optimization
English
TitleThe Administered Activity of Radionuclides in Nuclear Medicine - Rational Reduction of Medical Radiation Exposure -
SubtitleOriginal Articles
AuthorsMototoshi NAKAMURA*, Sukehiko KOGA*, Takeshi KONDO**, Syuichi TACHIKI**, Hirofumi ANNO**, Kazutaka EJIRI**, Hiroshi TOYAMA*, Gen TAKESHITA*, Kaori NAKANE*, Mamoru TOKUDA***, Kimie YOKOYAMA****, Akira TAKEUCHI**
Authors(kana)
Organization*Department of Radiology, Fujita Health University School of Medicine, **Department of Radiological Technology, Fujita Health University School of Health Sciences, ***Department of Internal Medicine, Fujita Health University School of Medicine, ****Department of Radiology, Fujita Health University Hospital
JournalThe Japanese Journal of nuclear medicine
Volume30
Number3
Page295-301
Year/Month1993/3
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractA survey of 104 hospitals was conducted to determine the administered activity of radionuclides. Eighty-five hospitals responded, and reported a total of 119,614 examinations in one year. The examinations included: bone scintigraphy, 26.4%; Thallium-201 (201Tl) myocardial scintigraphy, 15.5%; Gallium-67 (67Ga) scintigraphy, 13.3%; N-isopropyl-p-[123I]iodoamphetamine (IMP) brain perfusion scintigraphy, 7.0%. The administered activity was corrected by body weight only for children at more than 80% of the responding hospitals. The number of hospitals that reported over-administration of radionuclide varied according to the type of scintigraphy performed: bone, 76%; inflammatory (67Ga), 93%; myocardial (201Tl), 89.2%; brain (IMP), 8.5%. The administered activity of IMP was closer to the upper limits specified in the Recommendations on Standardization of Radionuclide Imaging by the Japan Radioisotope Association (1987), because IMP is very expensive and is supplied as single vials. The highest average effective dose was for myocardial scintigraphy, the second-highest for inflammatory scintigraphy, and the third-highest for bone scintigraphy. In 201Tl and 67Ga scintigraphy, the entire contents of the vial may be administered two days before the expiration date, because the ratio of (true patient administered activity) to (declared patient administered activity) is similar to the ratio of (radioactivity on the day of supply) to (radioactivity on the day of expiration). The factors that influence administered activity are throughput, price of the radionuclide, and whether the radionuclide is sold as a single vial. In order to decrease the effective dose, it is necessary to establish a close cooperation between medical personnel, the makers of radiopharmaceuticals, and manufactures of gammacameras.
PracticeClinical medicine
KeywordsRadionuclide, Administrations and Dosage, Radiation protection, Optimization

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