| Japanese |
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| Title | 131I-MIBGシンチグラフィによる褐色細胞腫の診断 - 手術例を中心に偽陰性例の検討も加えて - |
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| Subtitle | 原著 |
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| Authors | 辻明徳*, 下村修*, 冨口静二*, 古嶋昭博*, 原正史*, 木下留美*, 大山洋一*, 高橋睦正* |
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| Authors(kana) | |
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| Organization | *熊本大学医学部放射線科教室 |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 3 |
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| Page | 241-247 |
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| Year/Month | 1993/3 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 褐色細胞腫18例, 本態性高血圧症25例に131I-MIBG scintigraphyを施行した. 各臓器別の131I-MIBGの集積の程度を見ると, 褐色細胞腫群では本態性高血圧症群に比べて, 心臓の集積が有意に低下しており, また, 陽性例と偽陰性例の間には腫瘍と心臓の集積の間に逆相関が見られた. 褐色細胞腫18例中, 腫瘍部の集積は4例6部位で偽陰性となり, sensitivity 78%, specificity 100%, accuracy 90%となった. 偽陰性例のCT, 手術所見による検討では, 腫瘍が小さいものだけでなく嚢胞状で充実性部分が非常に少ない腫瘍や全体が出血壊死に陥った腫瘍などに偽陰性が見られた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 131I-MIBG scintigraphy, Pheochromocytoma |
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| English |
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| Title | Diagnosis of Pheochromocytoma Using 131I-MIBG Scintigraphy |
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| Subtitle | Original Articles |
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| Authors | Akinori TSUJI*, Osamu SHIMOMURA*, Seiji TOMIGUCHI*, Akihiro KOJIMA*, Masashi HARA*, Rumi KINOSHITA*, Youichi OOYAMA*, Mutsumasa TAKAHASHI* |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Kumamoto University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 3 |
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| Page | 241-247 |
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| Year/Month | 1993/3 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | 131I-MIBG scintigraphy was performed on 18 patients with pheochromocytoma and 25 patients with essential hypertension. In comparison of grade of 131I-MIBG accumulation in various organs the heart accumulation of pheochromocytoma group was significantly lower than that of essential hypertension group. And between the positive and false negative accumulation group of pheochromocytoma reverse relationship was observed between the heart and tumor. The results of 131I-MIBG scintigraphy for pheochromocytoma included 78% sensitivity, 100% specificity, and 90% accuracy. False negative accumulation of tumors were shown at 6 lesions in 4 cases. On the bases of CT and operative findings, false negative accumulation was observed not only in very small tumors, but also in large cystic tumors with a small amount of tumor tissue or totally hemorrhagic necrosis within the tumor. |
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| Practice | Clinical medicine |
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| Keywords | 131I-MIBG scintigraphy, Pheochromocytoma |
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