Japanese
Title洞不全症候群における左室収縮・拡張特性の障害とペーシング負荷時の左室機能 - 心プールシンチ平衡時マルチゲート順方向・逆方向収集法による検討 -
Subtitle原著
Authors松村憲太郎*, 中瀬恵美子*, 長谷川章**, 灰山徹**
Authors(kana)
Organization*京都南病院内科, **京都南病院放射線科
Journal核医学
Volume30
Number2
Page151-159
Year/Month1993/2
Article原著
Publisher日本核医学会
Abstract「要旨」心プールシンチグラフィ平衡時マルチゲート順方向・逆方向収集法を用いて, 洞不全症候群における左室機能を心房・心室順次ペーシング下に検討した. 洞不全症候群では安静時にすでに左室最大駆出速度, 最大充満速度が有意に低下しており, ペーシング負荷で最大駆出速度がさらに低下する症例では左室拡張特性がより強く障害されていた. 冠動脈に有意な器質的狭窄がなく, ほかに心筋障害を疑わせる合併症や既往症もない洞不全症候群における左室機能障害の原因は不明であるが, 冠攣縮性狭心症合併例と非合併例では, 安静時の左室血行動態である左室駆出分画, 最大駆出速度, 最大充満速度は冠攣縮性狭心症合併例で有意に低下していた. 洞不全症候群に冠攣縮性狭心症を合併する症例では生理的ペーシングを施行しても十分な左室機能の改善が得られない可能性がある.
Practice臨床医学：一般
KeywordsSick sinus syndrome, Vasospastic angina, Cardiac pool scintigraphy, A-V sequential pacing, Left ventricular hemodynamics
English
TitleLeft Ventricular Hemodynamics in Patients with Sick Sinus Syndrome : Analysis by 99mTc-RBC Cardiac Pool Scintigraphy with Forward and Backward Multiple Gated Method (FBMG)
SubtitleSummary
AuthorsKentaro MATSUMURA*, Emiko NAKASE*, Akira HASEGAWA**, Tohru HAIYAMA**
Authors(kana)
Organization*Department of Internal Medicine, **Department of Radiology, Kyoto Minami Hospital
JournalThe Japanese Journal of nuclear medicine
Volume30
Number2
Page151-159
Year/Month1993/2
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractThe left ventricular (LV) systolic and diastolic functions in 31 patients with sick sinus syndrome (types I and II) were analyzed using LV time activity curves obtained by a 99mTc-RBC cardiac pool scintigraphy-forward and backward multiple gated study (FBMG) and compared with those in controls. On A-V sequential pacing (rate, 70 bpm; A-V delay, 150 msec), LV-peak ejection rate (PER) and peak filling rate (PFR) were significantly decreased compared to those in normal controls. As pacing rate was increased, PFR decreased significantly in patients in whom PER was decreased. The etiology of disturbed LV systolic and diastolic functions in patients with sick sinus syndrome remains unknown. No patient had significant organic coronary artery disease or other cardiac disorder. On the other hand, the frequency of vasospastic angina was higher in this group than in the controls. We suspect that sick sinus syndrome and vasospastic angina probably share a common pathophysiology. In patients with sick sinus syndrome, LV systolic and diastolic functions are impaired at rest and during A-V sequential pacing.
PracticeClinical medicine
KeywordsSick sinus syndrome, Vasospastic angina, Cardiac pool scintigraphy, A-V sequential pacing, Left ventricular hemodynamics

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