| Japanese |
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| Title | 99mTc標識PPN−1011による虚血性心疾患急性期再灌流療法の効果判定 |
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| Subtitle | 短報 |
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| Authors | 西田佳雄*, 渡辺佐知郎*, 松尾仁司*, 琴尾泰典*, 小田寛*, 松原徹夫*, 杉山明*, 松野由起彦*, 加納素夫*, 谷畠進太郎*, 大橋宏重*, 後藤明**, 牧田一成**, 渡辺浩志**, 水谷豪利**, 三宅浩**, 今枝孟義*** |
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| Authors(kana) | |
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| Organization | *県立岐阜病院循環器科・腎臓科, **中央放射線部, ***岐阜大学医学部放射線科 |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 1 |
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| Page | 79-83 |
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| Year/Month | 1993/1 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」急性心筋梗塞 (AMI) や不安定狭心症 (UAP) など急性心筋虚血に対するPTCA/PTCRの効果判定に対する99mTc PPN-1011の有用性を評価した. AMI2例, UAP2例に対し, PTCA/PTCR前に99mTc PPN-1011を555MBq投与し術後に撮像を行った. PTCA/PTCR後像は血行再建後7-35日に静注し, 30-60分後に撮像した. 全例において術前に認められた灌流欠損領域の縮小ないし消失を認めた. 急性心筋虚血領域および再灌流療法の効果が99mTc PPN-1011により評価可能と考えられた. 「I. はじめに」虚血性心疾患の診断と重症度の判定に心筋シンチグラフィは現在日常臨床の場では確立された唯一の方法で, 特に心筋viabilityの判定に重要な情報を与える. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc PPN-1011, Acute myocardial infarction, Area at risk, PTCA, PTCR. |
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| English |
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| Title | Perfusion Imaging with 99mTc PPN-1011 for the Assessment of Myocardial Area at Risk and the Efficacy of PTCA / PTCR in Myocardial Infarction and Unstable Angina |
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| Authors | Yoshio NISHIDA*, Sachiro WATANABE*, Hitoshi MATSUO*, Yasunori KOTOO*, Hiroshi ODA*, Tetsuo MATSUBARA*, Akira SUGIYAMA*, Yukihiko MATSUNO*, Motoo KANO*, Shintaro TANIHATA*, Hiroshige OOHASHI*, Akira GOTOH*, Kazunari MAKITA*, Hiroshi WATANABE*, Taketoshi MIZUTANI*, Hiroshi MIYAKE*, Takeyoshi IMAEDA** |
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| Authors(kana) | |
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| Organization | *Division of Cardiology and Radiology, Prefectural Gifu Hospital, **Department of Radiology, Gifu University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 1 |
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| Page | 79-83 |
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| Year/Month | 1993/1 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]The determination of the myocardium at risk before intervention and the change in that region after intervention constitute a promising measurement tool for the assessment of acute therapy. We used 99mTc PPN-1011 in 4 patients with acute myocardial ischemia (2 patients with acute myocardial infarction, 2 unstable angina) and subsequent successful reperfusion. All 4 patients had perfusion defect on the pre-reperfusion image. Perfusion abnormality on post-reperfusion image was all improved significantly compared with prereperfusion image, suggesting the efficacy of acute treatment in acute myocardial ischemia. We conclude that 99mTc PPN-1011 scintigraphy is useful method for the assessment of myocardial area at risk and the efficacy of PTCA/PTCR in myocardial infarction and unstable angina. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc PPN-1011, Acute myocardial infarction, Area at risk, PTCA, PTCR. |
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