| Japanese |
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| Title | 膵癌治療後の効果判定における201TlCl SPECTの有用性 |
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| Subtitle | 短報 |
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| Authors | 藤田岳史*, 菅一能*, 中田太志*, 米城秀*, 内迫博路*, 中西敬*, 濱中祐一郎**, 鈴木敬**, 宇津見博基***, 山田典将*** |
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| Authors(kana) | |
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| Organization | *山口大学医学部放射線科, **第二外科, ***附属病院放射線部 |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 1 |
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| Page | 75-78 |
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| Year/Month | 1993/1 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」201TlCl SPECTによる膵癌治療の効果判定を3例に試みた. 腫瘍への201TlClの集積度を腫瘍/肝の集積比で検討すると, いずれの症例も集積比の変動と腫瘍マーカーのCA19-9の変動との間に相関を認めた. このうち1例ではCT上, 治療後も腫瘍の大きさに変化を認めないが, 集積比は低下し, かつCA19-9値の低下を伴っていた. これらの結果から201TlCl SPECTが膵癌治療の効果判定に応用できる可能性が示唆された. 「I. はじめに」現在, 膵癌に対する核医学検査は, 腫瘍を陽性描画する有効な放射性医薬品がなく, 積極的には行われていない. しかし, Thallium-201 chloride(201TlCl)の腺癌への親和性を応用して, 1991年に戸川らはSPECTを用い膵癌での比較的高い陽性率を報告した. 今回, さらに膵癌の治療効果判定にも201TlCl SPECT検査が応用できる可能性が示唆されたので報告する. |
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| Practice | 臨床医学：一般 |
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| Keywords | 201TlCl, SPECT, Pancreatic cancer, Radiation. |
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| English |
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| Title | Usefulness of 201TlCl SPECT for Evaluation of Treatment Effect of Pancreatic Cancer |
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| Subtitle | |
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| Authors | Takeshi FUJITA*, Kazuyoshi SUGA*, Taishi NAKADA*, Shigeru YONESHIRO*, Hiromichi UCHISAKO*, Takashi NAKANISHI*, Yuichiro HAMANAKA**, Takashi SUZUKI**, Hiromoto UTSUMI***, NorimasaYAMADA*** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Yamaguchi University School of Medicine, **Second Department of Surgery, Yamaguchi University School of Medicine, ***Department of Radiology, Yamaguchi University Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 1 |
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| Page | 75-78 |
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| Year/Month | 1993/1 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]To assess the treatment effect of pancreatic cancer, thallium 201 chloride (201TlCl) SPECT was performed in three patients. All of the patients before and after treatment showed the same change between the tumor/liver uptake ratio of 201TlCl and the serum level of CA 19-9. In one of the patients, tumor shrinkage was not observed on CT. However, the uptake ratio decreased, accompanying with a reduced serum level of CA 19-9. These results indicate that 201TlCl SPECT is useful to evaluate therapeutic effect of pancreatic cancer. |
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| Practice | Clinical medicine |
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| Keywords | 201TlCl, SPECT, Pancreatic cancer, Radiation. |
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