| Japanese |
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| Title | 小児心筋血流SPECTによる先天性心疾患の評価 : 各疾患における右室圧 / 左室圧比の推定の精度 |
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| Subtitle | 原著 |
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| Authors | 石井巌*,†, 中嶋憲一*, 滝淳一*, 谷口充*, 分校久志*, 利波紀久*, 久田欣一*, 大野高史** |
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| Authors(kana) | |
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| Organization | *金沢大学医学部核医学科, **小児科, †現在東京医科大学放射線科 |
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| Journal | 核医学 |
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| Volume | 30 |
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| Number | 1 |
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| Page | 41-49 |
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| Year/Month | 1993/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」小児先天性心疾患における右室圧/左室圧比と201Tl右室/左室集積比の相関の疾患別特徴および意義を検討した. 装置は平行またはファンビームコリメータを装着した高分解能3検出器型SPECTを用いた. 全102症例での右室/左室の圧比と平均集積比の相関はplanar像, SPECT像ともに良好であった(それぞれr=0.89および0.80, p=0.0001). SPECT像の201Tl集積の定量的解析は各疾患群で右室負荷の様式により特徴的な結果を示した. 疾患別の一次回帰の比較では特に心室中隔欠損症で相関が良好であった. また複合心奇形でも軽度の正相関(r=0.51, p=0.05)を示し, 同様に右室圧推定は可能であると考えられた. さらにファロー四徴症および肺動脈弁狭窄症の術後症例では201Tl右室/左室集積比の低下が右室負荷の改善の程度を明瞭に示した. 以上より本法は小児先天性心疾患における右室圧推定の良好な指標となると結論された. |
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| Practice | 臨床医学：一般 |
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| Keywords | 201Tl SPECT, Congenital heart disease, Right ventricular pressure, Pediatric patients, Right ventricular overload. |
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| English |
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| Title | Assessment of Congenital Heart Disease by a Thallium-201 SPECT Study in Children : Accuracy of Estimated Right to Left Ventricular Pressure Ratio |
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| Subtitle | Original Articles |
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| Authors | Iwao ISHII*, Kenichi NAKAJIMA*, Junichi TAKI*, Mitsuru TANIGUCHI*, Hisashi BUNKO*, Norihisa TONAMI*, Kinichi HISADA*, Takashi OHNO** |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine, **Department of Pediatrics, Kanazawa University Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 30 |
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| Number | 1 |
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| Page | 41-49 |
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| Year/Month | 1993/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]The characteristics of correlation between the right-to-left ventricular systolic pressure ratios (RVp/LVp) and the thallium-201 right-to-left ventricular (201Tl R/L) count ratios was investigated in children with various congenital heart diseases. High-resolution three-headed SPECT system equipped with either parallel-hole or fan-beam collimators was used. In a total of 102 patients, the correlation between RVp/LVp and 201Tl R/L average count ratios was good in both planar (r=0.89, p=0.0001) and SPECT studies (r=0.80, P=0.0001). Quantitative analysis of myocardial uptake by SPECT demonstrated the characteristic pattern of each disease as well as the differences in the right ventricular overload types. When the linear regression analysis was performed in each heart disease, ventricular septal defect showed most excellent correlation. Complex heart anomalies also showed positive correlation (r=0.51, p=0.05) with RVp/LVp, and it can be used to estimate right ventricular pressure. After surgical treatment of tetralogy of Fallot and pulmonary stenosis, the decrease of 201Tl R/L count ratio was in accordance with improvement of right ventricular overload. We conclude that 201Tl SPECT study can be a good indicator for estimation of right ventricular pressure. |
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| Practice | Clinical medicine |
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| Keywords | 201Tl SPECT, Congenital heart disease, Right ventricular pressure, Pediatric patients, Right ventricular overload. |
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